Tham C.Y., Poon L.F.,…Osato M. and Li S. High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform. Nat. Comm. 2023 Jan 17 14(1):281. doi: 10.1038/s41467-023-35823-7 

Nargund A.M.,… Li S.* and Tan P.* (Co-corresponding author) Chromatin Alterations Driven by MSH2 Deficiency Confer Cell Adhesion Deregulation and Sensitivity to BET Inhibition. 2022 Cancer Research 82(14):2538-2551 doi: 10.1158/0008-5472.CAN-21-2072 

Fan X,…Li S, …Low A. CXCL5 administration dampens inflammation and improves survival in murine lupus via myeloid and neutrophil pathways. Arthritis & Rheumatology 2022 Oct 14 doi:10.1002/art.42383 

Cai Y., …Li S, ... and Fullwood M.J. H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interaction. 2021 Nature Communications 12:1 doi: 10.1038/s41467-021-20940-y. 

Choo, XY,… Li S,... and Rackham O.J.L. Evaluating capture sequence performance for single-cell CRISPR activation experiments. ACS Synthetic Biology 2021 10(3), 640-645. doi:10.1021/acssynbio.0c00499. 

Xing M…Li S, Teh BT, and Tan P Genomic and epigenomic EBF1 alterations modulate Tert expression in gastric cancer. Journal of Clinical Investigation 2020 130(6):3005-3020 doi:10.1172/JCI126726. 

Yi Wei, B., Yeh ChingLin, Yeow Tee Goh, Li S., Liam Pock Ho, Tumor infiltrating lymphocytes from acute myeloid leukemia marrow can be reverted to CD45RA+ central memory state by reactivation in SIP (Simulated Infective Protocol). Immunobiology 224 (4), 526-531. (2020)

Xu, C.;  Ooi, W. F.;  Qamra, A.;  Tan, J.;  Chua, B. Y.-J.;  Ho, S. W. T.;  Das, K.;  Adam Isa, Z. F.;  Li, Z.;  Yao, X.;  Yan, T.;  Xing, M.;  Huang, K. K.;  Lin, J. S.;  Nandi, T.;  Tay, S. T.;  Lee, M. H.;  Tan, A. L. K.;  Ong, X.;  Ashktorab, H.;  Smoot, D.;  Li S.;  Ng, S.-C.;  Teh, B. T.; Tan, P., HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer. Gut 69 (2), 231-242. (2020)

Ooi, W. F.;  Nargund, A. M.;  Lim, K. J.;  Zhang, S.;  Xing, M.;  Mandoli, A.;  Lim, J. Q.;  Ho, S. W. T.;  Guo, Y.;  Yao, X.;  Lin, S. J.;  Nandi, T.;  Xu, C.;  Ong, X.;  Lee, M.;  Tan, A. L.-K.;  Lam, Y. N.;  Teo, J. X.;  Kaneda, A.;  White, K. P.;  Lim, W. K.;  Rozen, S. G.;  Teh, B. T.;  Li, S.;  Skanderup, A. J.; Tan, P., Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma. Gut, gutjnl-2018-317612. (2019)

Cai, Y.;  Zhang, Y.;  Loh, Y. P.;  Tng, J. Q.;  Lim, M. C.;  Cao, Z.;  Raju, A.;  Li S.;  Manikandan, L.;  Tergaonkar, V.;  Tucker-Kellogg, G.; Fullwood, M. J., H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions. bioRxiv, 684712. (2019)

TingDong, Y.;  Wen Fong, O.;  Qamra, A.;  Cheung, A.;  Ma, D.;  Gopinath Meenakshi, S.;  Chang, X.;  Xing, M.;  Poon, L.;  Wang, J.;  Loh, Y. P.;  Jess Hui Jie, H.;  Joscelyn Jun Quan, N.;  Muhammad Khairul, R.;  Aswad, L.;  Rozen, S. G.;  Ghosh, S.;  Bard, F. A.;  Sampath, P.;  Tergaonkar, V.;  Davies, J. O. J.;  Hughes, J. R.;  Goh, E.;  Bi, X.;  Fullwood, M. J.;  Tan, P.; Li S., HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis. Nature Communications 9, 1. (2018)

Fan, X.;  Guo, D.;  Cheung, A. M. S.;  Poon, Z. Y.;  Yap, C. S.;  Goh, S. E.;  Guo, D.;  Li, H.;  Bari, S.;  Li S.;  Lim, K. H.; Hwang, W. Y. K., Mesenchymal Stromal Cell (MSC)-Derived Combination of CXCL5 and Anti-CCL24 Is Synergistic and Superior to MSC and Cyclosporine for the Treatment of Graft-versus-Host Disease. Biology of Blood and Marrow Transplantation 24 (10), 1971-1980. (2018)

Bari, S.;  Zhong, Q.;  Fan, X.;  Poon, Z.;  Lim, A. S. T.;  Lim, T. H.;  Dighe, N.;  Li S.;  Chiu, G. N. C.;  Chai, C. L. L.; Hwang, W. Y. K., 199 - Ex Vivo Expansion of SCID-Repopulating CD34+CD90+CD49f+Hematopoietic Stem & Progenitor Cells From Non-Enriched Human Umbilical Cord Blood with Novel Azole-Based Small Molecules. Biology of Blood and Marrow Transplantation 24 (3, Supplement), S189. (2018)

Bari, S.;  Zhong, Q.;  Fan, X.;  Poon, Z.;  Lim, A. S. T.;  Lim, T. H.;  Dighe, N.;  Li S.;  Chiu, G. N. C.;  Chai, C. L. L.; Hwang, W. Y. K., Ex Vivo Expansion of CD34+CD90+CD49f+ Hematopoietic Stem and Progenitor Cells from Non-Enriched Umbilical Cord Blood with Azole Compounds. STEM CELLS Translational Medicine 7 (5), 376-393. (2018)

Yao, X.;  Tan, J.;  Lim, K. J.;  Koh, J.;  Ooi, W. F.;  Li, Z.;  Huang, D.;  Xing, M.;  Chan, Y. S.;  Qu, J. Z.;  Tay, S. T.;  Wijaya, G.;  Lam, Y. N.;  Hong, J. H.;  Lee-Lim, A. P.;  Guan, P.;  Ng, M. S. W.;  He, C. Z.;  Lin, J. S.;  Nandi, T.;  Qamra, A.;  Xu, C.;  Myint, S. S.;  Davies, J. O. J.;  Goh, J. Y.;  Loh, G.;  Tan, B. C.;  Rozen, S. G.;  Yu, Q.;  Tan, I. B. H.;  Cheng, C. W. S.;  Li S.;  Chang, K. T. E.;  Tan, P. H.;  Silver, D. L.;  Lezhava, A.;  Steger, G.;  Hughes, J. R.;  Teh, B. T.; Tan, P., VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma. Cancer Discovery 7 (11), 1284. (2017)

Ramlee, M. K.;  Wang, J.;  Cheung, A. M. S.; Li S., Using a Fluorescent PCR-capillary Gel Electrophoresis Technique to Genotype CRISPR/Cas9-mediated Knockout Mutants in a High-throughput Format. J Vis Exp (122), 55586. (2017)

Gopalakrishnan, V.; Tan, C. R.; Li S., Sequential phosphorylation of CST subunits by different cyclin-Cdk1 complexes orchestrate telomere replication. Cell Cycle 16 (13), 1271-128. (2017)

Arya, D.;  Sachithanandan, S. P.;  Ross, C.;  Palakodeti, D.;  Li S.; Krishna, S., MiRNA182 regulates percentage of myeloid and erythroid cells in chronic myeloid leukemia. Cell death & disease 8 (1), e2547-e2547. (2017)

Ooi, W. F.;  Xing, M.;  Xu, C.;  Yao, X.;  Ramlee, M. K.;  Lim, M. C.;  Cao, F.;  Lim, K.;  Babu, D.;  Poon, L.-F.;  Lin Suling, J.;  Qamra, A.;  Irwanto, A.;  Qu Zhengzhong, J.;  Nandi, T.;  Lee-Lim, A. P.;  Chan, Y. S.;  Tay, S. T.;  Lee, M. H.;  Davies, J. O. J.;  Wong, W. K.;  Soo, K. C.;  Chan, W. H.;  Ong, H. S.;  Chow, P.;  Wong, C. Y.;  Rha, S. Y.;  Liu, J.;  Hillmer, A. M.;  Hughes, J. R.;  Rozen, S.;  Teh, B. T.;  Fullwood, M. J.;  Li S.; Tan, P., Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity. Nature Communications 7, 12983. (2016)

Liu, C. C.;  Ma, D. L.;  Yan, T.-D.;  Fan, X.;  Poon, Z.;  Poon, L.-F.;  Goh, S.-A.;  Rozen, S. G.;  Hwang, W. Y. K.;  Tergaonkar, V.;  Tan, P.;  Ghosh, S.;  Virshup, D. M.;  Goh, E. L. K.; Li S., Distinct Responses of Stem Cells to Telomere Uncapping—A Potential Strategy to Improve the Safety of Cell Therapy. STEM CELLS 34 (10), 2471-2484. (2016)

Khattar, E.;  Kumar, P.;  Liu, C. Y.;  Akıncılar, S. C.;  Raju, A.;  Lakshmanan, M.;  Maury, J. J. P.;  Qiang, Y.;  Li S.;  Tan, E. Y.;  Hui, K. M.;  Shi, M.;  Loh, Y. H.; Tergaonkar, V., Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression. J Clin Invest 126 (10), 4045-4060. (2016)

Ramlee, M. K.;  Yan, T.;  Cheung, A. M. S.;  Chuah, C. T. H.; Li S., High-throughput genotyping of CRISPR/Cas9-mediated mutants using fluorescent PCR-capillary gel electrophoresis. Scientific Reports 5, 15587. (2015)

Koh, C. M.;  Khattar, E.;  Leow, S. C.;  Liu, C. Y.;  Muller, J.;  Ang, W. X.;  Li, Y.;  Franzoso, G.;  Li S.;  Guccione, E.; Tergaonkar, V., Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity. J Clin Invest, 125 (5), 2109-2122. (2015)

Akıncılar, S. C.;  Low, K. C.;  Liu, C. Y.;  Yan, T. D.;  Oji, A.;  Ikawa, M.;  Li S.; Tergaonkar, V., Quantitative assessment of telomerase components in cancer cell lines. FEBS Letters 589 (9), 974-984. (2015)

Liu, C.-C.;  Gopalakrishnan, V.;  Poon, L.-F.;  Yan, T.; Li S., Cdk1 regulates the temporal recruitment of telomerase and Cdc13-Stn1-Ten1 complex for telomere replication. Molecular and cellular biology 34 (1), 57-70. (2014)

Xu, L.;  Li S.; Stohr, B. A., The Role of Telomere Biology in Cancer. Annual Review of Pathology: Mechanisms of Disease 8 (1), 49-78. (2013)

Ho, L. P.;  Yit, P. S.;  Ng, L. H.;  Linn, Y. C.;  Zhao, Y.;  Sun, L.;  Ling, K. L.;  Chai Koh, M. B.;  Monica Shih, M.-C.;  Li S.;  Wang, X. Y.;  Tien, S. L.; Goh, Y. T., The Road to Memory: An Early Rest for the Long Journey. The Journal of Immunology  191 (11), 5603. (2013)

Bari, S.;  Chu, P. P. Y.;  Lim, A.;  Fan, X.;  Gay, F. P. H.;  Bunte, R. M.;  Lim, T. K. H.;  Li S.;  Chiu, G. N. C.; Hwang, W. Y. K., Protective role of functionalized single walled carbon nanotubes enhance ex vivo expansion of hematopoietic stem and progenitor cells in human umbilical cord blood. Nanomedicine: Nanotechnology, Biology and Medicine 9 (8), 1304-1316. (2013)

Ghosh, A.;  Saginc, G.;  Leow, S. C.;  Khattar, E.;  Shin, E. M.;  Yan, T. D.;  Wong, M.;  Zhang, Z.;  Li, G.;  Sung, W.-K.;  Zhou, J.;  Chng, W. J.;  Li S.;  Liu, E.; Tergaonkar, V., Telomerase directly regulates NF-κB-dependent transcription. Nature Cell Biology 14 (12), 1270-1281. (2012)

Li S.., Cell-cycle-dependent telomere elongation by telomerase in budding yeast. Bioscience Reports 2011, 31 (3), 169-177. (2011)

Li S.;  Makovets, S.;  Matsuguchi, T.;  Blethrow, J. D.;  Shokat, K. M.; Blackburn, E. H., Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression. Cell, 136 (1), 50-61. (2009)

Li S.;  Nosrati, M.; Kashani-Sabet, M., Knockdown of Telomerase RNA Using Hammerhead Ribozymes and RNA Interference. In Telomerase Inhibition: Strategies and Protocols, Andrews, L. G.; Tollefsbol, T. O., Eds. Humana Press: Totowa, NJ, pp 113-131. (2007)

Bagheri, S.;  Nosrati, M.;  Li S.;  Fong, S.;  Torabian, S.;  Rangel, J.;  Moore, D. H.;  Federman, S.;  Laposa, R. R.;  Baehner, F. L.;  Sagebiel, R. W.;  Cleaver, J. E.;  Haqq, C.;  Debs, R. J.;  Blackburn, E. H.; Kashani-Sabet, M., Genes and pathways downstream of telomerase in melanoma metastasis. Proceedings of the National Academy of Sciences of the United States of America 103 (30), 11306-11311. (2006)

Li S.;  Crothers, J.;  Haqq, C. M.; Blackburn, E. H., Cellular and Gene Expression Responses Involved in the Rapid Growth Inhibition of Human Cancer Cells by RNA Interference-mediated Depletion of Telomerase RNA. Journal of Biological Chemistry 280 (25), 23709-23717. (2005)

Nosrati, M.;  Li S.;  Bagheri, S.;  Ginzinger, D.;  Blackburn, E. H.;  Debs, R. J.; Kashani-Sabet, M., Antitumor Activity of Systemically Delivered Ribozymes Targeting Murine Telomerase RNA. Clinical Cancer Research  10 (15), 4983. (2004)

Li S.;  Rosenberg, J. E.;  Donjacour, A. A.;  Botchkina, I. L.;  Hom, Y. K.;  Cunha, G. R.; Blackburn, E. H., Rapid Inhibition of Cancer Cell Growth Induced by Lentiviral Delivery and Expression of Mutant-Template Telomerase RNA and Anti-telomerase Short-Interfering RNA. Cancer Research 64 (14), 4833. (2004)

Zheng, L.;  Pan, H.;  Li S.;  Flesken-Nikitin, A.;  Chen, P.-L.;  Boyer, T. G.; Lee, W.-H., Sequence-Specific Transcriptional Corepressor Function for BRCA1 through a Novel Zinc Finger Protein, ZBRK1. Molecular Cell 6 (4), 757-768. (2000)

Li S.;  Ting, N. S. Y.;  Zheng, L.;  Chen, P.-L.;  Ziv, Y.;  Shiloh, Y.;  Lee, E. Y. H. P.; Lee, W.-H., Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature 406 (6792), 210-215. (2000)