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Liu Yu-Chi

Associate Professor

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Education Qualifications: MCI, MD, PhD

A/Prof Liu Yu-Chi completed her resident training in Ophthalmology and fellowship training in Cornea and External Eye Diseases in Taiwan, and obtained the specialist accreditation in Ophthalmology in 2009 before she joined Singapore Eye Research Institute (SERI) in 2012.  Currently, she is appointed as Clinician Scientist and Principal Investigator in SERI and Singapore National Eye Centre (SNEC).  She is also the Deputy Head of Tissue Engineering and Cell Therapy Group. Her research focuses on corneal and external eye diseases, particularly in corneal neuropathy and corneal imaging.   

A/Prof Liu’s research work leads to 106 peer-reviewed publications, including two in prestigious journals: LANCET and LANCET RESPIRATORY MEDICINE. Among these publications, she is the first author or last author in 54 articles. 23 of her publications are published in top 10% journals, and 40 of her publications are in top 20% journals. She has been awarded 13 independent national or institutional grants, including NMRC Clinician Scientist Award (CSA), Transition Award (TA).  She also won 16 international and national awards, including the Achievement Award, Asia-Pacific Academy of Ophthalmology (2019), Distinguished Young Researcher Award, SingHealth (2019), Best Presentation and Best Paper Awards, Asia-Pacific Association of Cataract and Refractive Surgeons (2021), and 1st Prize Presentation Award, European Society of Cataract & Refractive surgeons Congress (2015), for my research and clinical work.  Her grants generated 2 patents on corneal imaging and more intellectual properties are expected. Besides the publications and grants, she is also actively involved in international academic activities.  She is on the Editorial Board as the Editor for 4 journals. She was invited to participate in writing 4 book chapters as the first author, including two in the leading textbook in the field of Cornea. 

A/Prof Liu has over 100 international invited talks and presentations. As a clinician scientist that has dual training in both ophthalmology and science, she believes the ultimate career goal is to advance and improve the diagnosis and treatment of patients through high-quality clinical and translational research.

Professional Appointments and Committee Memberships:

  • Education Committee, Taiwan Society of Cataract and Refractive Surgeons (2022-Present)
  • Member, Asian Dry Eye Society (2017-Present)
  • Member and Scientific Review Panel, Asia-Pacific Academy of Ophthalmology (2010-Present)
  • Member, Asia-Pacific Association of Cataract and Refractive Surgeons (2011-Present)
  • Member, Asia Cornea Society (2015-Present)
  • Member, Association for Research in Vision and Ophthalmology, USA (2009-Present)
  • Member, American Academy of Ophthalmology (2011-Present)
  • Member, American Society of Cataract and Refractive Surgeons (2011-Present)
  • Member, European Society of Cataract & Refractive Surgeons (2013-Present)
  • Member, Association for Cataract and Refractive Surgery, Taiwan (2006-Present)
  • Member, Taiwan Ophthalmological Society (2006-Present)
  • Member, Asia Pacific Association of Cataract & Refractive Surgeons (2011-Present)
  • Member, Women in Ophthalmology (2018-Present)

Awards:

  • Clinician Scientist Award, National Medical Research Council, Singapore (2022)
  • Best Poster Award (Refractive Surgery Category), Asia-Pacific Association of Cataract and Refractive Surgeons (APACRS) Congress (2021)
  • Best Poster Award (Cataract Surgery Category), Asia-Pacific Association of Cataract and Refractive Surgeons (APACRS) (2021)
  • Awardee of Academic Development Program, Asia-Pacific Academy of Ophthalmology (APAO) (2021)
  • Achievement Award, Asia-Pacific Academy of Ophthalmology (2019)
  • Distinguished Young Researcher Award, SingHealth (2019)
  • National Medical Research Council Fellowship/Scholarship, Singapore (2018)
  • Transition Award, National Medical Research Council, Singapore (2017)
  • 1st Prize Presentation Award, European Society of Cataract and Refractive Surgeons (ESCRS) Congress (2015)
  • Outstanding Fellow Award, Singapore Eye Research Institute (2015)
  • Travel Grant Award, World Ophthalmology Congress (WOC) (2014)
  • ExxonMobil-NUS Research Fellowship for Clinicians Award (2013)
  • Healthcare Research Scholarship Award, Ministry of Health (2013)
  • First in National Board Ophthalmology Examination, Taiwan (2009)
  • Best Resident Oral Presentation, 48th Annual Meeting of Taiwan Ophthalmological Society (2008)
  • Academic Top Scholarship (class standing: number one), Taipei Medical University, Taiwan (2003)
  • Excellent Scholarship (class standing: top five), Shui-Wang Ho Medical Foundation, Taipei Medical University, Taiwan (2001-2004)

Leadership positions / roles in Education: 

  • Deputy Head, Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute

Research Interests: 

  • Corneal Diseases
  • Corneal Neuropathy
  • Corneal Imaging

Selected 10 Publications:

108 Peer-Reviewed Papers.  54 as First/Last/Corresponding author

H index: 25; Citation: 2138; i10 index: 54 (as of 23 July 2022)

1. Liu Yu-Chi; Wilkins Mark; Kim Terry; Malyugin Boris; Mehta Jodhbir S. Cataracts. Lancet (London, England) 2017;
390(10094):600-612. JIF: 79.32.

2. Liu Yu-Chi, Ang M, Ong HS, Wong TY, Mehta JS. SARS-CoV-2 infection in conjunctival tissue. Lancet Respiratory
Medicine 2020; 87(7):e57. JIF: 30.70.

3. Liu Yu-Chi; Rosman Mohamad; Mehta Jodhbir. Enhancement after Small-Incision Lenticule Extraction: Incidence, Risk Factors, and Outcomes. Ophthalmology 2017; 124(6):813-821. JIF: 12.08.

4. Liu Yu-Chi, Yam YH, MTY Lin, Teo PW, Koh SW, Deng L, Zhou L, Tong L, Mehta JS. Comparison of tear proteomic and
neuromediator profiles changes between small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis. Journal of Advanced Research 2020;29:67-81. JIF: 10.48.

5. Liu Yu-Chi, TY Lin, AHC Ang, TT Wong, Mehta JS. Nanotechnology for the treatment of allergic conjunctival diseases. Pharmaceuticals 2020; 13(11):351. JIF: 5.86.

6. Liu Yu-Chi; Devarajan Kavya; Tan Tien-En; Ang Marcus; Mehta Jodhbir S. Optical Coherence Tomography Angiography for Evaluation of Reperfusion After Pterygium Surgery. American journal of ophthalmology 2019; 207:151-158. JIF: 5.49.

7. Liu Yu-Chi; Lin Molly Tzu-Yu; Mehta Jodhbir S. Analysis of corneal nerve plexus in corneal confocal microscopy images.
Neural regeneration research 2021; 16(4):690-691. JIF: 6.06.

8. Yang LWY, Mehta JS, Liu Yu-Chi. Corneal neuromediator profiles following refractive surgery. Neural Regeneration Research 2021;16(11):2177-83 JIF: 6.06.

9. So WZ, Wong SQ, Tan HC, Mehta JS, Liu Yu-Chi. Diabetic cornea neuropathy as the surrogate marker for diabetic peripheral neuropathy. Neural Regen Res 2022;17(10):2172-78. JIF: 6.06

10. Liu Yu-Chi, Melina Setiawan, Jia Ying Chin, Benjamin Wu, Hon Shing Ong, Ecosse Lamoureux, Jodhbir S. Mehta. Randomized Controlled Trial Comparing 1-year Outcomes of Low-energy Femtosecond Laser-Assisted versus Conventional Cataract Surgery. Frontiers of Medicine 2021; 8: 811093. JIF: 5.09.