LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AWT Ng, AB Boot, KR Covington, DA Gordenin, E Bergstrom, N Lopez-Bigas, LJ Klimczak, JR McPherson, S Morganella, S Sabarinathan, DA Wheeler, V Mustonen, the PCAWG Mutational Signatures Working Group, G Getz, SG Rozen*, MR Stratton*, PCAWG Consortium. "The repertoire of mutational signatures in human cancer" Nature 578 94-101,
https://doi.org/10.1038/s41586-020-1943-3 (2020) (* = corresponding author) IF 43.07
J Zavadil, SG Rozen. "Experimental Delineation of Mutational Signatures Is an Essential Tool in Cancer Epidemiology and Prevention" Chemical Research in Toxicology, 32:2153-2155 (2019) IF 3.278
EN Bergstrom, MN Huang, U Mahto, M Barnes, MR Stratton, SG Rozen, LB Alexandrov. "SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events" BMC Genomics 20, doi: 10.1186/s12864-019-6041-2 (2019) IF 3.730
Y.S. Low, C. Bloecker, J.R. McPherson, S.A. Tang, Y.Y. Cheng, J.Y.S. Wong, C. Chua, T.K.H. Lim, C.L. Tang, M.H. Chew, P.T. Tan, I.B. Tan*, S.G. Rozen*, P.Y. Cheah*. "A formalin-fixed paraffin-embedded (FFPE)-based prognostic signature to predict metastasis in clinically low risk stage I/II microsatellite stable colorectal cancer" Cancer Lett 403:3-20 (2017) (* = corresponding author) IF 5.62
M.N. Huang, W. Yu, W.W. Teoh, M. Ardin, A. Jusakul, A. Ng, A. Boot, B. Abedi-Ardekani, S. Villar, S.S .Myint, R .Othman, S.L. Poon, A. Heguy, M. Olivier, M. Hollstein, P. Tan, B.T. Teh, K. Sabapathy, J. Zavadil, S. Rozen. "Genome-scale mutational signatures of aflatoxin in cells, mice and human tumors" Genome Res, doi:10.1101/gr.220038.116 (2017) IF 11.35
A. Jusakul, I. Cutcutache, C.H. Yong, J.Q. Lim, M.N. Huang, N. Padmanabhan, V. Nellore, S. Kongpetch, A.W.T. Ng, L.M. Ng, S.P. Choo, S.S. Myint, R. Thanan, S. Nagarajan, W.K. Lim, C.C.Y. Ng, A. Boot, M. Liu, C.K. Ong, V. Rajasegaran, S. Lie, AS-T Lim, T.H. Lim, J. Tan, M.J. Liang, J. Mcpherson, N. Khuntikeo, V. Bhudhisawasdi, P. Yongvanit, S. Wongkham, Y. Totoki, H. Nakamura, Y. Arai, S. Yamasaki, P. Chow, A.Y.F. Chung, L.L.P.J .Ooi, T. Lim, S. Dima, D. Duda, I. Popescu, P. Broet, S-Y Hsieh, M-C Yu, A. Scarpa, J. Lai, D. Luo, A.L. Carvalho, A. Vettore, H. Rhee, Y.N. Park, L. Alexandrov, R. Gordan*, S .Rozen*, T. Shibata*, C. Pairojkul*, B.T. Teh*, P. Tan*. "Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma" Cancer Discov, doi:10.1158/2159-8290.CD-17-0368 (2017) (* = corresponding author) IF 19.78
Y. Suzuki, S.B. Ng, C. Chua, W.Q. Leow, J. Chng, S.Y. Liu, K. Ramnarayanan, A. Gan, D.L. Ho, R. Ten, Y. Su, A. Lezhava, J. H. Lai, D. Koh, K.H. Lim, P. Tan, S.G Rozen*, I.B. Tan* "Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer" Mol Oncol doi:10.1002/1878-0261.12012 (2016) (* = corresponding author) IF 5.37
J. Tan, C.K. Ong, W.K. Lim, C.C.Y. Ng, A.A. Thike, L.M. Ng, V. Rajasegaran, S.S. Myint, S. Nagarajan, S. Thangaraju, S. Dey, N.D. Md Nasir, G.C. Wijaya, J.Q. Lim, D. Huang, Z. Li, B.H. Wong, J.Y.S. Chan, J.R. McPherson, I. Cutcutache, G. Poore, S.T. Tay, W.J. T. Tan, C. Putti, B.S. Ahmad, P. Iau, C.W. Chan, A.P.T. Tang, W.S. Yong, P. Madhukumar, G.H. Ho, V.K.M. Tan, C.Y. Wong, M. Hartman, K.W. Ong, B.K.T. Tan, S.G. Rozen*, P. Tan*, P.H. Tan*, B.T. Teh*. "Genomic landscapes of breast fibroepithelial tumors" Nat Genet 47:1341–1345 (2015) (* = corresponding author) IF 29.35
I. Cutcutache, A.Y. Wu, Y. Suzuki, J.R. McPherson, Z. Lei, N. Deng, S. Zhang, W.K. Wong, K.C. Soo, W.H. Chan, L.L. Ooi, R. Welsch, P. Tan, S.G. Rozen. "Abundant copy-number loss of CYCLOPS and STOP genes in gastric adenocarcinoma" Gastric Cancer 1-13 (2015) IF 3.71
I. Cutcutache, Y. Suzuki, I. B. Tan, S. Ramgopal, S. Zhang, K. Ramnarayana, A. Gan, H.H. Lee, S.T. Tay, A. Ooi, C.K. Ong, J.T. Bolthouse, B.R. Lane, J.G. Anema, R.J. Kahnoski, P. Tan*, B.T. Teh*, S.G. Rozen*. "Exome-wide sequencing shows low mutation rates and identifies novel mutated genes in seminomas" Eur. Urol. 68(1):77-83 (2015) (* = corresponding author). Designated "Platinum Priority" and highlighted in a journal editorial. IF 13.93
S.L. Poon, M.N. Huang, Y. Choo, J.R. McPherson, W. Yu, H.L. Heng, A. Gan, S.S. Myint, E.Y. Siew, L.D. Ler, L.G. Ng, W.-H. Weng, C.-K. Chuang, J.S.P Yuen, S.-T. Pang*, P. Tan*, B.T. Teh*, S.G. Rozen*. "Mutation signatures implicate aristolochic acid in bladder cancer development" Genome Med. 7:38 (2015) (* = corresponding author) IF 4.94
W.K. Lim, C.K. Ong, J. Tan, A.A. Thike, C.C. Ng, V. Rajasegaran, S.S. Myint, S. Nagarajan, N.D. Nasir, J.R. McPherson, I. Cutcutache, G. Poore, S.T. Tay, W.S. Ooi, V.K. Tan, M. Hartman, K.W. Ong, B.K. Tan, S.G. Rozen*, P.H. Tan*, P. Tan*, B.T. Teh*. "Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma” Nat. Genet. 46:877-880 (2014) (* = corresponding author) IF 29.6
S.L. Poon, J.R. McPherson, P. Tan, B.T. Teh, S.G. Rozen. "Genome wide carcinogen signatures promise new opportunities for cancer prevention" Genome Med. (review) 6:24 (2014) IF 4.9
Z. Lei, I.B. Tan, K. Das, N. Deng, H. Zouridis, S. Pattison, C. Chua, Z. Feng, Y.K. Guan, C.H. Ooi, T. Ivanova, S. Zhang, M. Lee, J. Wu, A. Ngo, S. Manesh, E. Tan, B.T. Teh, J.B. Yan So, L.K. Goh, A. Boussioutas, T.K. Hon Lim, H. Flotow, P. Tan, S.G. Rozen. "Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase Inhibitors and 5-fluorouracil” Gastroenterology 145:554-565 (2013) (received journal editorial) IF 13.9
S.L. Poon, S.-T. Pang*, J.R. McPherson, W. Yu, K.K. Huang, P. Guan, W.-H. Weng, E.Y. Siew, Y. Liu, H..L. Heng, S.C. Chong, A. Gan, S.T. Tay, W.K. Lim, I. Cutcutache, D. Huang, L.D. Ler, M.-L. Nairismägi, M.H. Lee, Y.-H. Chang, K.-J. Yu, W. Chan-on, B.-K. Li, Y.-F. Yuan, C.-N. Qian, K.-F. Ng, C.-F. Wu, C.-L. Hsu, R. M. Bunte, M.R. Stratton, P.A. Futreal, W.-K. Sung, C.-K. Chuang, C.K. Ong, S.G. Rozen*, P. Tan*, B.T. Teh* "Genome wide mutational signatures of aristolochic acid and its application as a screening tool. " Sci. Transl. Med. 5:197ra101 (2013) (Received journal cover image and focus article; also highlighted by Science Magazine and The Scientist; (* = corresponding author) IF 14.4
A. Untergasser, I. Cutcutache, T. Koressaar, J. Ye, B.C. Faircloth, M. Remm, S.G. Rozen. "Primer3 - New capabilities and interfaces” Nucleic Acids Res. 40:e115 (2012) IF 8.3