Bio
Assistant Professor Yeo Joo Guan (MBBS, MMed, MRCPCh (UK), PhD) is a Senior Consultant in Paediatric Medicine at KK Women’s and Children’s Hospital, a Clinician Scientist at the Translational Immunology Institute (TII), SingHealth Duke-NUS Academic Medical Centre and the Vice-Chair (Research), SingHealth Duke NUS Paediatrics Academic Clinical Programme. He earned his MBBS and Master of Medicine (Paediatric Medicine) from the National University of Singapore (NUS). He is dually trained as a specialist paediatrician and scientist in immunology. During his advanced speciality training, he obtained his PhD from the Department of Microbiology, Immunology programme, NUS, on the role of serine protease C1s in lupus pathogenesis supported by the Ministry of Health's Healthcare Research Scholarship in 2014. With this dual background as a paediatrician and scientist, he has an intimate knowledge of the disease-associated dysfunction and ontogeny of the immune system. This enables him to contribute positively to the development of machine-learning tools for the mining of immunological data with a translational perspective that ensued clinical relevance.
Following the completion of his advanced speciality training in 2015, he was mentored by Professor Salvatore Albani with the support of the Academic Medicine Research Institute's Khoo Clinical Scholar Program for 1 year, working on the holistic, multi-dimensional interrogation of the immunome of childhood-onset Systemic Lupus Erythematosus with the dual translational goals of identifying predictors of clinical fate and novel therapeutic targets for manipulation. The pilot results from this study have resulted in the successful application for the National Medical Research Council's Transition Award during the November 2016 grants call with the project entitled: "Interrogation of Childhood-Onset Systemic Lupus Erythematosus Immunome for the Elucidation of Disease." Currently, he holds two active NMRC grants, CSA-INV and CS-IRG, to study the mechanism underpinning the development of autoimmunity and the impact of an auto-reactive milieu on the responses to mRNA vaccines.
Education
Doctor of Philosophy
National University of Singapore, Singapore
Member, Royal Coll of Paediatrics & Child Health
Royal College of Paediatrics and Child Health, United Kingdom
Master of Medicine (Paediatrics)
National University of Singapore, Singapore
Bachelor of Medicine, Bachelor of Surgery
National University of Singapore, Singapore