Walk along the Level 7 corridor in Duke-NUS, and the burst of colour from one particular office is sure to catch your eye. Canvases awash in myriad blues, icy whites and glimmers of gold swirl with ethereal movement, charming you through the door, an extension of the person within.
“From first impressions, people might think I have it all figured out,” said Assistant Professor Ann-Marie Chacko, the creator of that unique space. “But honestly, there are moments of intense self-doubt.”
Chacko joined Duke-NUS from the US ten years ago, hired specifically to run a new joint corporate lab under the National Research Foundation Corp Lab @ University scheme, leading research collaborations and services in an academic setting. “It was a trial by fire in so many ways, being new to Singapore, but then learning business, finance and contracting, when this was my first job,” she said. “I knew my science but wow, all this responsibility!”
When the joint lab ended, Chacko pivoted to create her own independent research lab, the Laboratory for Translation and Molecular Imaging, specialising in nuclear medicine. “Simply put, we are developing radioactive molecules that can noninvasively detect disease and treat disease,” explained Chacko, with her lab’s focus on creating innovations for cancer and viral infection.
Drawing on her scientific expertise as a chemist and pharmacologist, and her newly acquired business acumen, she plugs into more than just government funding to advance her research: “I am a believer in adding value to research through partnerships, including industry. Hence, it was important to me to maintain the service element of my lab to facilitate the really exciting science here in Singapore and beyond.”
And being one of the few labs licensed to handle radioactive materials, her team’s expertise are in high demand as they advance the field of radiotheranostics. “It’s about thinking outside the box as I try to balance the needs of the community with the need to create impact in my own research programme, in consideration of my career advancement and that of my trainees.”
Looking back at the ingredients essential to her success, Chacko notes that learning how to silence self-doubt was—and still is—the biggest internal challenge.
“It’s recalling that you’ve come so far and you have achieved so much,” she said.
But having champions around you is also important: “We hear a lot about mentorship and mentors are important as they guide you through the swampy waters,” she said. “But who is your champion when you’re not in the room? Who will advocate for you, connect you with the people you need to know? They’re the ones who can speak for you when you’re not at the table.”
Among her team, she cultivates a work environment of empowerment, where team members, regardless of seniority, are trusted to make big decisions, take risks, safe in the knowledge that she has their back: “It’s natural that we may make mistakes, so long as we try to learn from them. Looking back at those mentors who have given me the space to grow, it’s through being more hands-off. And I try to bring that growth-mindset ethos to the lab whenever I can.”