Joint Faculty Staff Details



Low Guek Hong Jenny

Professor, Centre for Clinician-Scientist Plus Development

Academic Vice Chair (Research), SingHealth Duke-NUS Medicine Academic Clinical Programme

Duke-NUS Medical School

Bio

Prof Jenny Low is a board-certified senior consultant with the Department of Infectious Diseases in the Singapore General Hospital and a Professor in the Programme in Emerging Infectious Diseases at Duke-NUS Medical School.  Concurrently, she is the Deputy Medical and Scientific Director of the SingHealth Investigation Medicine Unit. Her research interest is to develop pathways for rapid bench-to-bedside translation of vaccines and therapeutics against acute viral diseases. Her approach is to combine novel trial design with state-of-the-art molecular investigations to generate deep data that enrich first-in-human and early phase clinical trials. Towards this goal, she co-founded and co-directs the Viral Research and Experimental Medicine Centre, SingHealth Duke-NUS Academic Medical Centre (ViREMiCS) to develop relevant molecular assays into ISO-accredited tests to support the translation of new vaccines and therapeutics into licensed products. This approach has been used to evaluate both small molecules as well as therapeutic antibodies against flaviviral diseases, such as dengue, Zika and yellow fever. More recently, she has expanded on this experimental medicine approach to rapidly develop a deeper understanding Covid-19 and the host response to SARS-CoV-2 infection, the knowledge of which was used to evaluate investigator-initiated and industry-sponsored therapeutic strategies and vaccine candidates against Covid-19. These efforts, apart from contributing to knowledge, have also increased Singapore’s profile as a preferred site for early phase, proof-of-concept clinical trials for acute viral diseases. She has authored and co-authored more than 100 publications in peer-reviewed journals and has more than 5000 citations with H-index of 35 and i10-index of 59. She has been awarded the Singapore National Medical Research Council Clinician-Scientist Award in 2016 and 2019. For her contribution, she has also received a series of research awards from SingHealth/Duke-NUS since 2014.

Education

Master of Science (Public Health)

Johns Hopkins University, United States

Master of Medicine (Internal Medicine)

National University of Singapore, Singapore

Member, Royal Coll of Physicians

Royal College of Physicians, UK, United Kingdom

Bachelor of Medicine, Bachelor of Surgery

National University of Singapore, Singapore

NUS Appointment(s)

Clinical Senior Lecturer

NUS, Yong Loo Lin School of Medicine, Currently Active

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