Back
NBD Seminar Series: Next generation GRAB sensors to spy on dopamine dynamics in vivo (via Zoom)
Abstract:
Dopamine (DA) is a crucial neurotransmitter involved in many physiological and pathological processes. Genetically-encoded GRAB sensors for dopamine are powerful new tools for measuring DA dynamics with high spatiotemporal precision in vivo. Here by tapping into different species and DA receptor subtypes, we rationally optimized a family of green and red fluorescent DA sensors with improved performance, opening doors to study neurochemical signals and modulatory effects on neural circuits.
Join Zoom Meeting
https://nus-sg.zoom.us/j/83484533172?pwd=VGYrZDRqdURmeHpUaGZET2ZNSDAzZz09
Meeting ID: 834 8453 3172
Passcode: 202755
Host:
Asst Prof Alfred Sun
Principal Investigator
Neuroscience & Behavioural Disorders Programme, Duke-NUS
Contact Person:
Joyceline Ng (joyceline.ng@duke-nus.edu.sg)
Neuroscience & Behavioural Disorders Programme, Duke-NUS
Date and Time
14 May 2021 @ 12:00 - 14 May 2021 @ 13:00
Speaker
Dr Yulong Li
Professor
School of Life Sciences
Peking University
China
Yulong Li is a professor at the School of Life Sciences of Peking University, PKU-THU Center for Life Sciences and PKU-IDG/McGovern Institute for Brain Research. He obtained his B.D. from PKU and Ph.D. from Duke Univ. He then conducted his postdoctoral research at Stanford Univ. His group pioneered the development and application of genetically-encoded fluorescent sensors, capable to detect the release of dopamine, acetylcholine, norepinephrine and adenosine with high spatiotemporal resolution.