Research Incubator


The Lien Centre for Palliative Care (LCPC) set up a “Research Incubator” in February 2013 with the aim of fostering an environment that generates high quality collaborative palliative care research. This model recognizes the wealth of clinical and scientific talent in palliative care but also the high constraints and competing priorities faced by palliative care providers. Therefore the research incubator is structured to take advantage of the best minds in palliative care research while minimizing the burden of overseeing research projects. It does this by offering a team of highly trained research staff who can assist the PI with many aspects of the research. This will allow for supporting community efforts to engage in innovative palliative care research while continuing to deliver high quality palliative care services.

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    What does research incubator do?

    The incubator will provide support via direct funding, manpower, subject matter and research expertise, and other resources for budgeting. IRB submission, project management, data collection, statistical analysis and manuscript writing required to jump-start and sustain high quality and innovative palliative care research projects in Singapore that are likely to have a real world impact. It will be overseen by Eric Finkelstein, the Executive Director of LCPC, and benefit from input by faculty of Duke-NUS, SingHealth, and local and international experts in palliative care research.

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    What are the research themes?

    Priority for funding will be given to the following four areas identified in National Strategy for Palliative Care as having significant gaps in the current knowledge base:

    1. Understanding and meeting patient/caregiver preferences regarding end-of-life care
    2. Communication at the end of life
    3. End-of-life care financing and delivery models
    4. Pain and symptom management at the end of life
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    Are there any funding priorities?

    Due to availability of limited funding, priority will be given to projects that

    1. Fall within the listed research priorities
    2. Are likely to impact end of life care in Singapore
    3. Are likely to generate high quality research outputs, including publications in top field and/or high impact journals
    4. Provide training opportunities for aspiring palliative care researchers
    5. Are likely to better position the PI for future research studies
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    Who is eligible?

    Any Singapore- based researcher in any field, with a primary appointment in a local public hospital/public health institution/ public university/academic medical centre and salaried by the institution, is eligible to apply as Principal Investigator (PI), as are researchers external to Singapore who plan to conduct the research in Singapore and have at least one Singapore-based Co-Investigators on their research team.

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    What happens when a PI submits a research proposal to LCPC?

    Prospective PIs will be encouraged to discuss potential research ideas with a Senior LCPC research team member of their choosing and/ or a member of AMRI to see if the idea may be worth pursuing as a research project. If the idea has potential and the PI would like to pursue LCPC support, he/she will be required to submit a two-page research proposal to LCPC research staff for review.

    The proposal, once received, will be screened by a senior LCPC research team member. The LCPC research team member will provide feedback and if the PI remains interested, will schedule the proposal for a presentation at an LCPC research forum (note-these forums may be held jointly with AMRI). PIs will prepare the presentation and send it to LCPC research team member for review and comment prior to the presentation at the research forum. This will ensure that the proposed research benefits from early feedback prior to the forum presentation.

    The primary goal of the forums is to provide feedback to the PI, with the aim of improving the proposed research plan. Based on the feedback, PIs of promising proposals will likely be asked to make modifications and to expand the research plan and, if requested, to make additional forum presentation(s). A proposal may also be rejected (meaning no LCPC staff or funds will support the project) after the first or second presentation, if despite feedback, it fails to meet standards for scientific merit and funding priorities.

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    How are proposals assessed?

    If shortlisted for funding consideration after the first or second presentation, the PI will likely be asked to submit a revised presentation and proposal and to prepare a project budget with help from the business manager at LCPC. The revised proposal and presentation will be sent to a local LCPC Research Advisory Board (LRAB) for review and scoring. All proposals will be scored by the LRAB based on scientific merit and funding priorities. Proposals with total costs (direct plus indirect) above $150,000 will be sent to an external advisory board (ERAB) for further review and comment. This secondary review is intended to ensure that the research is internationally competitive and that the funding represents a good investment for LCPC. The external review is expected to take no more than one month. It may generate additional requests for modifications to the research proposal and require additional forum presentations. The LCPC Director will decide, on a quarterly basis, which of the highly scored proposals to fund based on the feedback received from the Research Director and advisory boards and on budget availability. Proposals not approved for funding can be resubmitted to LCPC after taking into account the recommendations of LRAB/ERAB.

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    What happens after my proposal is approved for funding?

    The proposals will be funded and the PI will be responsible for carrying out the proposed work. As the LCPC research incubator will include data collectors, writing, analytical, and budgeting support, and other infrastructure requirements necessary for carrying out high quality research, the PI will be strongly encouraged to take advantage of the LCPC resources rather than hiring her own staff. We would also encourage the PI to include at least one LCPC researchers as a Co-investigator if that would strengthen the research. The PI or a delegate will also be expected to make regular updates on the project status at the research forums. This will provide an opportunity to address any concerns that may arise with the research in a timely manner.

    We strongly believe that an incubator approach provides the best strategy for cost-effectively generating high-quality research outputs and encourage interested researchers to bounce ideas off the LCPC research team and to submit applications.

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    How to apply

    We look forward to hearing more about your research projects. Please contact us if you have any queries or to further explore your research ideas:

    Eric Finkelstein: eric.finkelstein@duke-nus.edu.sg

    LCPC Grant Application Template

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    Recent LCPC Incubator Grants Awarded

    Title Start Date End Date PI Amount Funded (S$)
    Impact of ACP on End of Life Care for Patients with Advanced Cancer and Heart Failure 1/12/2014 30/11/2023 Chetna Malhotra (Duke-NUS) 150,000.00
    Communications Quality between Physicians and Cancer Patients in Singapore 1/12/2014 30/11/2024 Chetna Malhotra (Duke-NUS) 125,000.00
    Costs and Medical Care of Patients with Advanced Serious Illness in Singapore Study 18/1/2016 17/1/2024 Eric Finkelstein (Duke-NUS) 579,000.00
    Development and validation of a quality of life scale in English and Chinese for family caregivers of patients with advanced cancers in Singapore 1/6/2016 31/5/2018 Cheung Yin Bun (Duke-NUS) 97,500.00
    Pilot Study of the SPARK (Supportive and Palliative Care Review Kit) model of care for advanced cancer patients who have an unplanned admission to Singapore General Hospital 30/9/2016 30/6/2017 Grace Yang (NCCS) 29,000.00
    Health Communication and Treatment Choice Among Elderly End Stage Renal Disease (ESRD) Patients 27/3/2017 26/9/2018 Helena Legido-Quigley (NUS) 47,500.00
    Challenges and Unmet Supportive Care Needs of LVAD Patients, LVAD Eligible Patients and their Caregivers 1/2/2018 1/2/2019 Shirlyn Neo (NCCS) 9,800.00
    Humanism Aspirations as a Propeller of Professional Development in Palliative medicine Education 1/7/2018 30/6/2019 Ong Eng Koon (NCCS) 6,500.00
    Development and validation of a quality of life measurement scale in English and Chinese for caregivers of people living with dementia in Singapore 1/1/2019 31/12/2019 Cheung Yin Bun (Duke-NUS) 45,500.00
    Experience and perceptions of medical futility at the end of life in Cardiology: a qualitative study with healthcare professionals 1/1/2020 30/6/2021 Nicholas Graves (Duke-NUS) 27,000.00
    Singapore Cohort of Patients with advanced heart failure (SCOPAH) 1/4/2020 31/3/2024 Chetna Malhotra (Duke-NUS) 365,476.00
    Cultural adaptation of the ENABLE (Educate, Nurture, Advise, Before Life Ends) intervention for heart failure patients and caregivers in Singapore (ENABLE-HF-SG) 1/8/2020 31/5/2022 Shirlyn Neo (NCCS) 44,675.00
    TTSH OT Day - Occupational Therapy and Palliative Care – Adding Life to Days 1/11/2020 31/5/2021 Josephine Neo (TTS) 4,000.00
    PROactive Triggering of Early Care through Technology 1/12/2020 31/12/2022 Zhuang Qingyuan (NCCS) 54,000.00
    Singapore Caregiver Quality of Life Scale 15-item Version 1/1/2021 31/12/2022 Cheung Yin Bun (Duke-NUS) 60,000.00
    Panel study investigating Status of Cognitively Impraired Elderly in Singapore 1/6/2021 31/5/2024 Chetna Malhotra (Duke-NUS) 200,000.00
    Cultural adaptation of the Serious Illness Conversation Guide for seriously ill patients in Singapore 1/1/2023 31/12/2023 Shirlyn Neo (NCCS) 31,100.00
    An Exploration of the Lived Experiences of Home and Day Hospice Patients with End-Stage Chronic Lung disease 1/1/2023 31/12/2023 Celine Yong (Assisi Hospice) 4,540.00
    Identifying the psychosocial and spiritual needs of patients in a local home hospice setting 1/9/2023 31/12/2024 Ooi Yinn Shan (Assisi Hospice) 9,940.00
    Transitions from Inpatient Hospice: Perspectives from Caregivers 1/5/2024 1/6/2025 Sandy Koh (OCH) 15,300.00
    Exploring the feasibility and acceptability of implementing the Psycho-existential Symptom Assessment Scale in a home-based palliative care setting 1/9/2024 25/9/2025 Dr Jonathan Ee (HCA) 33,882.00

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