This section gives an overview of the commonly used drugs (excluding opioids) to manage symptoms in patients with terminal illnesses. The information includes basic dosage information as well as indications for use and potential side effects. Please note that non-opioid drugs commonly used in palliative care in Singapore are shown here but the list is NOT exhaustive and neither are the side effects nor indications. Doses are for adults only. Please check with pharmacy colleagues for dose adjustments (if any) in renal or liver impairment. Unless otherwise indicated, use water for injection for dilution in continuous subcutaneous infusions.
*For information on opioids, please search and refer to the drugs with their given context.
Risperidone
Route, Dosage and Frequency
ROUTE
|
DOSAGE AND FREQUENCY
|
| PO |
0.5-2 mg at bedtime to b.d. (Drops/Tablets) (max dose 4mg/day) 0.25-0.5mg at bedtime (in elderly) |
Other Information
Indications
Delirium, Psychotic disorders.
Side-Effects
Insomnia, Agitation, Anxiety, Headache, Somnolence, Weight gain, Extrapyramidal symptoms (less than typical anti-psychotics).
Remarks
Atypical antipsychotic. Caution for use in patients with dementia (increased mortality), or Parkinson’s disease. Lowest risk of lowering seizure threshold among the atypical anti-psychotics.
Reference
- Watson M. Oxford Handbook of Palliative Care. Oxford, NY: Oxford University Press; 2009.