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Ng Heng Joo

Clinical Professor

Head & Senior Consultant, Haematology, Singapore General Hospital

Director, Clinical Governance and Quality, Office of Patient Safety and Quality, Singapore General Hospital

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Education Qualifications: MBBS, MMed (Int Med), MRCP(UK), FRCPath(UK),FAMS

Prof Ng received his early medical training at the National University of Singapore and then served in Malaysia before qualifying as an internal medicine specialist. He then joined the Department of Haematology for his advanced specialty training in haematology before pursuing subspecialty training in coagulation, a branch of haematology dealing with blood clotting and bleeding disorders.

He is currently the Head of the department.

Prof Ng has a special interest in thrombotic and bleeding disorders. His research activities cover clinical aspects of managing these patients and laboratory diagnostics into coagulation disorders.

Professional Appointments and Committee Memberships:

  • Head, Department of Haematology, Singapore General Hospital
  • Director, Clinical Governance and Quality, Office of Patient Safety and Quality, Singapore General Hospital
  • Visiting Consultant, Blood Services Group, Health Sciences Authority

Awards:

  • Master Academic Clinician 2024, Duke-NUS Medical School
  • Public Administration Medal (Bronze), National Day Award 2022
Research Interests: Thrombotic and bleeding disorders

Selected Publications:

1: Tan CW, Ho LP, Kalimuddin S, Cherng BPZ, Teh YE, Thien SY, Wong HM, Tern PJW, Chandran M, Chay JWM, Nagarajan C, Sultana R, Low JGH, Ng HJ. Cohort study to evaluate the effect of vitamin D, magnesium, and vitamin B12 in combination on progression to severe outcomes in older patients with coronavirus (COVID-19). Nutrition. 2020 Nov-Dec;79-80

2: Tan CW, Low JGH, Wong WH, Chua YY, Goh SL, Ng HJ. Critically ill COVID-19 infected patients exhibit increased clot wavefom analysis parameters consistent with hypercoagulability. Am J Hematol. 2020 Jul;95(7):E156-E158. 

3: Fung FY, Wong WH, Ang SK, Koh HL, Kun MC, Lee LH, Li X, Ng HJ, Tan CW, Zhao Y, Linn YC. A randomized, double-blind, placebo- controlled study on the anti-haemostatic effects of Curcuma longa, Angelica sinensis and Panax ginseng.
Phytomedicine. 2017 Aug 15;32:88-96.

4: Reding MT, Ng HJ, Poulsen LH, Eyster ME, Pabinger I, Shin HJ, Walsch R, Lederman M, Wang M, Hardtke M, Michaels LA. Safety and efficacy of BAY 94-9027, a prolonged-half-life factor VIII. J Thromb Haemost. 2017 Mar;15(3):411-419.

5: Wang Y, Xie F, Kong MC, Lee LH, Ng HJ, Ko Y. Cost-effectiveness of dabigatran and rivaroxaban compared with warfarin for stroke prevention in patients with atrial fibrillation. Cardiovasc Drugs Ther. 2014 Dec;28(6):575-85.

6: Ng HJ, Than H, Teo EC. First experiences with the use of rivaroxaban in the treatment of heparin-induced thrombocytopenia. Thromb Res. 2015 Jan;135(1):205-7. 

7: Wang Y, Kong MC, Lee LH, Ng HJ, Ko Y. Knowledge, satisfaction, and concerns regarding warfarin therapy and their association with warfarin adherence and
anticoagulation control. Thromb Res. 2014 Apr;133(4):550-4. 

8: Lai YF, Cheen MH, Lim SH, Yeo FH, Nah SC, Kong MC, Mya D, Lee LH, Ng HJ. The effects of fasting in Muslim patients taking warfarin. J Thromb Haemost. 2014;12(3):349-54. 

9: Linn YC, Yong HX, Niam M, Lim TJ, Chu S, Choong A, Chuah C, Goh YT, Hwang W, Loh Y, Ng HJ, Suck G, Chan M, Koh M. A phase I/II clinical trial of autologous cytokine-induced killer cells as adjuvant immunotherapy for acute and chronic
myeloid leukemia in clinical remission. Cytotherapy. 2012 Aug;14(7):851-9. 

10: Ng HJ, Lee LH. Trends in prevalence of deep venous thrombosis among hospitalised patients in an Asian institution. Thromb Haemost. 2009 Jun;101(6):1095-9. 

11: Ang AL, Kuperan P, Ng CH, Ng HJ. Acquired factor V inhibitor. A problem-based systematic review. Thromb Haemost. 2009 May;101(5):852-9. 

12: Letchumanan P, Ng HJ, Lee LH, Thumboo J. A comparison of thrombotic thrombocytopenic purpura in an inception cohort of patients with and without systemic lupus erythematosus. Rheumatology (Oxford). 2009 Apr;48(4):399-403.

13: Kong MC, Lim TG, Ng HJ, Chan YH, Lee LH. Feasibility, cost-effectiveness and patients' acceptance of point-of-care INR testing in a hospital-based anticoagulation clinic. Ann Hematol. 2008 Nov;87(11):905-10. 

14: Ng HJ, Crowther MA. Azathioprine and inhibition of the anticoagulant effect of warfarin: evidence from a case report and a literature review. Am J Geriatr Pharmacother. 2006 Mar;4(1):75-7. 

15: Whitlock R, Crowther MA, Ng HJ. Bleeding in cardiac surgery: its prevention and treatment--an evidence-based review. Crit Care Clin. 2005 Jul;21(3):589-610.

16: Hwang WY, Koh LP, Ng HJ, Tan PH, Chuah CT, Fook SC, Chow H, Tan KW, Wong C, Tan CH, Goh YT. A randomized trial of amifostine as a cytoprotectant for patients receiving myeloablative therapy for allogeneic hematopoietic stem cell
transplantation. Bone Marrow Transplant. 2004 Jul;34(1):51-6. 

17: Ng HJ, Koh LP, Lee LH. Successful control of postsurgical bleeding by recombinant factor VIIa in a renal failure patient given low molecular weight heparin and aspirin. Ann Hematol. 2003 Apr;82(4):257-8. 

18: Ng HJ, Lim LC. Fulminant hepatitis B virus reactivation with concomitant listeriosis after fludarabine and rituximab therapy: case report. Ann Hematol. 2001 Sep;80(9):549-52. 

19: Tan CW, Tan JY, Wong WH, Cheong MA, Ng IM, Conceicao EP, Low JGH, Ng HJ, Lee LH. Clinical and laboratory features of hypercoagulability in COVID-19 and other
respiratory viral infections amongst predominantly younger adults with few comorbidities. Sci Rep. 2021 Jan 19;11(1):1793.