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Au Wing Lok

Associate Professor

Academic Chair, Neuroscience Academic Clinical Programme

Chief Executive Officer & Senior Consultant, Department of Neurology, National Neuroscience Institute

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Education Qualifications: MBBS (Singapore), MRCP (United Kingdom), FAMS (Neurology), FRCP (Edinburgh)

A/Prof Au graduated from the National University of Singapore, and received his neurology training at the National Neuroscience Institute.  After completing his Advanced Specialist Training, he underwent two years of Movement Disorders Fellowship at the Pacific Parkinson’s Research Centre in Vancouver, Canada. He was also trained in Electrophysiology in Movement Disorders at the Toronto Western Hospital, Toronto, Canada.

A/Prof Au specialises in the clinical care of patients with Parkinson disease and Movement disorders. He is trained in administering botulinum toxin injections to a wide range of movement disorders such as hemifacial spasm, blepharospasm, dystonia and spasticity. His research interests are in functional neuroimaging and electrophysiology in Parkinson disease.

Professional Appointments and Committee Memberships:

  • Senior Consultant, Department of Neurology, National Neuroscience Institute (Tan Tock Seng Hospital Campus)
  • Clinical Senior Lecturer, Yong Loo Lin School of Medicine
  • Clinical Teacher, Lee Kong Chian School of Medicine

Awards:

  • SingHealth Quality Service Award, 2016 (Silver)
  • Distinguished Team Award, SingHealth Excellence Award, 2015
  • HMDP Fellowship Award, SingHealth, 2012
  • NMRC Medical Research Fellowship Award, 2005
  • HMDP Fellowship Award, NHG, 2004 - 2005

Research Interests:

  • Functional Neuroimaging
  • Electrophysiology in Parkinson Disease

Selected Publications:

Au WL, Seah IS, Li W, Tan LC. Effects of Age and Gender on Hand Motion Tasks. Parkinsons Dis. 2015;2015:862427. Epub 2015 May 24.

Prakash BD, Sitoh YY, Tan LC, Au WL. Asymmetrical diffusion tensor imaging indices of the rostral substantia nigra in Parkinson's disease. Parkinsonism Relat Disord. 2012 Nov;18(9):1029-33. Epub 2012 Jun 16.

Au WL, Zhou J, Palmes P, Sitoh YY, Tan LC, Rajapakse JC. Levodopa and the feedback process on set-shifting in Parkinson's disease. Hum Brain Mapp. 2012 Jan;33(1):27-39. Epub 2011 Mar 24.

de la Fuente-Fernández R, Schulzer M, Kuramoto L, Cragg J, Ramachandiran N, Au WL, Mak E, McKenzie J, McCormick S, Sossi V, Ruth TJ, Lee CS, Calne DB, Stoessl AJ. Age-specific progression of nigrostriatal dysfunction in Parkinson's disease. Ann Neurol. 2011;69(5):803-810. Epub 2011 Jan 18.

Palmes P, Ang WT, Widjaja F, Tan LC, Au WL. Pattern mining of multichannel sEMG for tremor classification. IEEE Trans Biomed Eng. 2010 Dec;57(12):2795-805. Epub 2010 Sep 16.

Srinivasan S, Lok AW. Valproate-induced reversible hemichorea. Mov Disord. 2010 Jul 30;25(10):1511-2.

Palmer SJ, Lee PW, Wang ZJ, Au WL, McKeown MJ. theta, beta But not alpha-band EEG connectivity has implications for dual task performance in Parkinson's disease. Parkinsonism Relat Disord. 2010 Jul;16(6):393-7. Epub 2010 May 1.

Au WL, Lei N, Oishi MM, McKeown MJ. L-dopa induces under-damped visually guided motor responses in Parkinson's disease. Exp Brain Res. 2010 May;202(3):553-9. Epub 2010 Feb 9.

Wong YC, Au WL, Xu M, Ye J, Lim CC. Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients. Arch Neurol. 2007 Jul;64(7):1034-7.

Au WL, Calne DB. A reassessment of the Lewy body. Acta Neurol Taiwan. 2005 Jun;14(2):40-7.