Directory

SingHealth Duke-NUS Research Team Award (1st Prize)

SingHealth Duke-NUS AMC,2023

SingHealth Publish! Award

SingHealth Duke-NUS AMC,2023

Reviewers' Choice Abstract

American Society of Human Genetics,2019

Reviewers' Choice Abstract

American Society of Human Genetics,2016

Genomics, Bioinformatics, Digital health/mHealth, Machine learning applications in biomedical sciences, Precision medicine

Analysis of clinically relevant variants from ancestrally diverse Asian genomes.

Nature communications – Chan Sock Hoai; Bylstra Yasmin; Teo Jing Xian; Kuan Jyn Ling; Bertin Nicolas; Gonzalez-Porta Mar; Hebrard Maxime; Tirado-Magallanes Roberto; Tan Joanna Hui Juan; Jeyakani Justin; Li Zhihui; Chai Jin Fang; Chong Yap Seng; Davila Sonia; Goh Liuh Ling; Lee Eng Sing; Wong Eleanor; Wong Tien Yin; ; Prabhakar Shyam; Liu Jianjun; Cheng Ching-Yu; Eisenhaber Birgit; Karnani Neerja; Leong Khai Pang; Sim Xueling; Yeo Khung Keong; Chambers John C; Tai E-Shyong; Tan Patrick; Jamuar Saumya S; Ngeow Joanne; Lim Weng Khong (2022)

13 (1);

Beyond fitness tracking: The use of consumer-grade wearable data from normal volunteers in cardiovascular and lipidomics research.

PLoS biology – Lim Weng Khong; Davila Sonia; Teo Jing Xian; Yang Chengxi; Pua Chee Jian; Blöcker Christopher; Lim Jing Quan; Ching Jianhong; Yap Jonathan Jiunn Liang; Tan Swee Yaw; Sahlén Anders; Chin Calvin Woon-Loong; Teh Bin Tean; Rozen Steven G; Cook Stuart Alexander; Yeo Khung Keong; Tan Patrick (2018)

16 (2);

Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma.

Nature genetics – Lim Weng Khong; Ong Choon Kiat; Tan Jing; Thike Aye Aye; Ng Cedric Chuan Young; Rajasegaran Vikneswari; Myint Swe Swe; Nagarajan Sanjanaa; Nasir Nur Diyana Md; McPherson John R; Cutcutache Ioana; Poore Gregory; Tay Su Ting; Ooi Wei Siong; Tan Veronique Kiak Mien; Hartman Mikael; Ong Kong Wee; Tan Benita K T; Rozen Steven G; Tan Puay Hoon; Tan Patrick; Teh Bin Tean (2014)

46 (8); 877-80

High-Resolution Digital Phenotypes From Consumer Wearables and Their Applications in Machine Learning of Cardiometabolic Risk Markers: Cohort Study.

Journal of medical Internet research – Zhou Weizhuang; Chan Yu En; Foo Chuan Sheng; Zhang Jingxian; Teo Jing Xian; Davila Sonia; Huang Weiting; Yap Jonathan; Cook Stuart; Tan Patrick; Chin Calvin Woon-Loong; Yeo Khung Keong; Lim Weng Khong; Krishnaswamy Pavitra (NB: co-corresponding author) (2022)

24 (7);

Genomic landscapes of breast fibroepithelial tumors.

Nature genetics – Tan Jing; Ong Choon Kiat; Lim Weng Khong; Ng Cedric Chuan Young; Thike Aye Aye; Ng Ley Moy; Rajasegaran Vikneswari; Myint Swe Swe; Nagarajan Sanjanaa; Thangaraju Saranya; Dey Sucharita; Nasir Nur Diyana Md; Wijaya Giovani Claresta; Lim Jing Quan; Huang Dachuan; Li Zhimei; Wong Bernice Huimin; Chan Jason Yong Sheng; McPherson John R; Cutcutache Ioana; Poore Gregory; Tay Su Ting; Tan Wai Jin; Putti Thomas Choudary; Ahmad Buhari Shaik; Iau Philip; Chan Ching Wan; Tang Anthony P H; Yong Wei Sean; Madhukumar Preetha; Ho Gay Hui; Tan Veronique Kiak Mien; Wong Chow Yin; Hartman Mikael; Ong Kong Wee; Tan Benita K T; Rozen Steven G; Tan Patrick; Tan Puay Hoon; Teh Bin Tean (NB: co-first author) (2015)

47 (11); 1341-5

Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers.

Nature genetics – Chan-On Waraporn; Nairismägi Maarja-Liisa; Ong Choon Kiat; Lim Weng Khong; Dima Simona; Pairojkul Chawalit; Lim Kiat Hon; McPherson John R; Cutcutache Ioana; Heng Hong Lee; Ooi London; Chung Alexander; Chow Pierce; Cheow Peng Chung; Lee Ser Yee; Choo Su Pin; Tan Iain Bee Huat; Duda Dan; Nastase Anca; Myint Swe Swe; Wong Bernice Huimin; Gan Anna; Rajasegaran Vikneswari; Ng Cedric Chuan Young; Nagarajan Sanjanaa; Jusakul Apinya; Zhang Shenli; Vohra Priya; Yu Willie; Huang DaChuan; Sithithaworn Paiboon; Yongvanit Puangrat; Wongkham Sopit; Khuntikeo Narong; Bhudhisawasdi Vajaraphongsa; Popescu Irinel; Rozen Steven G; Tan Patrick; Teh Bin Tean (NB: co-first author) (2013)

45 (12); 1474-8

Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging.

Communications biology – Teo Jing Xian; Davila Sonia; Yang Chengxi; Hii An An; Pua Chee Jian; Yap Jonathan; Tan Swee Yaw; Sahlén Anders; Chin Calvin Woon-Loong; Teh Bin Tean; Rozen Steven G; Cook Stuart Alexander; Yeo Khung Keong; Tan Patrick; Lim Weng Khong (2019)

2

Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas.

Scientific reports – Chan Sock Hoai; Lim Weng Khong; Ishak Nur Diana Binte; Li Shao-Tzu; Goh Wei Lin; Tan Gek San; Lim Kiat Hon; Teo Melissa; Young Cedric Ng Chuan; Malik Simeen; Tan Mann Hong; Teh Jonathan Yi Hui; Chin Francis Kuok Choon; Kesavan Sittampalam; Selvarajan Sathiyamoorthy; Tan Patrick; Teh Bin Tean; Soo Khee Chee; Farid Mohamad; Quek Richard; Ngeow Joanne (NB: co-first author) (2017)

7 (1);

Identification of constrained sequence elements across 239 primate genomes.

Nature – Kuderna Lukas F K; Ulirsch Jacob C; Rashid Sabrina; Ameen Mohamed; Sundaram Laksshman; Hickey Glenn; Cox Anthony J; Gao Hong; Kumar Arvind; Aguet Francois; Christmas Matthew J; Clawson Hiram; Haeussler Maximilian; Janiak Mareike C; Kuhlwilm Martin; Orkin Joseph D; Bataillon Thomas; Manu Shivakumara; Valenzuela Alejandro; Bergman Juraj; Rouselle Marjolaine; Silva Felipe Ennes; Agueda Lidia; Blanc Julie; Gut Marta; de Vries Dorien; Goodhead Ian; Harris R Alan; Raveendran Muthuswamy; Jensen Axel; Chuma Idriss S; Horvath Julie E; Hvilsom Christina; Juan David; Frandsen Peter; Schraiber Joshua G; de Melo Fabiano R; Bertuol Fabrício; Byrne Hazel; Sampaio Iracilda; Farias Izeni; Valsecchi João; Messias Malu; da Silva Maria N F; Trivedi Mihir; Rossi Rogerio; Hrbek Tomas; Andriaholinirina Nicole; Rabarivola Clément J; Zaramody Alphonse; Jolly Clifford J; Phillips-Conroy Jane; Wilkerson Gregory; Abee Christian; Simmons Joe H; Fernandez-Duque Eduardo; Kanthaswamy Sree; Shiferaw Fekadu; Wu Dongdong; Zhou Long; Shao Yong; Zhang Guojie; Keyyu Julius D; Knauf Sascha; Le Minh D; Lizano Esther; Merker Stefan; Navarro Arcadi; Nadler Tilo; Khor Chiea Chuen; Lee Jessica; Tan Patrick; Lim Weng Khong; Kitchener Andrew C; Zinner Dietmar; Gut Ivo; Melin Amanda D; Guschanski Katerina; Schierup Mikkel Heide; Beck Robin M D; Karakikes Ioannis; Wang Kevin C; Umapathy Govindhaswamy; Roos Christian; Boubli Jean P; Siepel Adam; Kundaje Anshul; Paten Benedict; Lindblad-Toh Kerstin; Rogers Jeffrey; Marques Bonet Tomas; Farh Kyle Kai-How (2024)

625 (7996); 735-742