Directory

Best oral poster (Novel prognostic factors)

2022

Runner up (oral paper (translational)

NCIS,2019

Singapore Health Quality Service Award Gold

SingHealth Duke NUS AMC,2019

Distinguished Young Leader Award

SingHealth Duke NUS AMC,2018

Singapore Health Quality Service Award - Silver Award

Singapore Health Quality Service Award,2016

Best poster

National Taiwan University,2015

Collaboration Award

KK Hospital,2015

Best poster (clinical research)

KK Hospital,2015

Best oral paper

KK Hospital,2015

Outstanding Clinical Teacher Award

KK Hospital,2015

Service from the Heart Award

KK Hospital,2015

SingHealth Publish! Award (Medical Research)

SingHealth,2015

Best paper

International Society of Pediatric Surgical Oncology,2015

SingHealth Publish! Award (Medical Research)

SingHealth,2013

NMRC Research Training Fellowship (Overseas Research Attachment)

National Medical Research Council, Singapore,2012

College of Surgeons Gold medal in Paediatric Surgery

Academy of Medicine Singapore,2011

Best poster

International Society of Pediatric Surgical Oncology,2011

Best paper

International Society of Pediatric Surgical Oncology,2009

Targeting mutant dicer tumorigenesis in pleuropulmonary blastoma via inhibition of RNA polymerase I.

Translational research : the journal of laboratory and clinical medicine – Wong Megan Rui En; Lim Kia Hui; Hee Esther Xuan Yi; Chen Huiyi; Kuick Chik Hong; Aw Sze Jet; Chang Kenneth Tou En; Syed Sulaiman Nurfarhanah; Low Sharon Yy; Hartono Septian; Tran Anh Nguyen Tuan; Ahamed Summaiyya Hanum; Lam Ching Mei Joyce; Soh Shui Yen; Hannan Katherine M; Hannan Ross D; Coupland Lucy A; Loh Amos Hong Pheng (2023)

258 60-71

Combinatorial screening using orthotopic patient derived xenograft-expanded early phase cultures of osteosarcoma identify novel therapeutic drug combinations.

Cancer letters – Loh Amos H P; Stewart Elizabeth; Bradley Cori L; Chen Xiang; Daryani Vinay; Stewart Clinton F; Calabrese Christopher; Funk Amy; Miller Greg; Karlstrom Asa; Krafcik Fred; Goshorn David R; Vogel Peter; Bahrami Armita; Shelat Anang; Dyer Michael A (2019)

442 262-270

Neuroblastoma patient-derived cultures are enriched for mesenchymal gene signature and reflect individual drug response

Cancer Science – Hee E, Wong MK, Tan SH, Choo Z, Kuick CH, Ling S, Yong MH, Jain S, Lian DW, Ng EH, Yong YF, Ren MH, Sulaiman NS, Low SY, Chua YW, Syed MF, Lim TK, Soh SY, Iyer P, Seng MS, Lam JC, Tan EE, Chan MY, Tan AM, Chen Y, Chen Z, Chang KT, Loh AH (2020)

111 (10); 3780-3792

Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma.

Frontiers in oncology – Wong Rachel L Y; Wong Megan R E; Kuick Chik Hong; Saffari Seyed Ehsan; Wong Meng Kang; Tan Sheng Hui; Merchant Khurshid; Chang Kenneth T E; Thangavelu Matan; Periyasamy Giridharan; Chen Zhi Xiong; Iyer Prasad; Tan Enrica E K; Soh Shui Yen; Iyer N Gopalakrishna; Fan Qiao; Loh Amos H P (2021)

11

Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody.

Molecular therapy oncolytics – Loh Amos Hong Pheng; Thura Min; Gupta Abhishek; Tan Sheng Hui; Kuan Kelvin Kam Yew; Ang Koon Hwee; Merchant Khurshid; Chang Kenneth Tou En; Yon Hui Yi; Chen Yong; Cheng Mathew Hern Wang; Mahadev Arjandas; Ng Matthew Chau Hsien; Seng Michaela Su-Fern; Iyer Prasad; Chia Pei Ling; Soh Shui Yen; Zeng Qi (2023)

30 153-166

Clinical, pathological and loss of heterozygosity differences in Wilms tumors between Asian and non-Asian children.

International journal of cancer – Loke Benjamin N; Wong Meng Kang; Tawng Khawn D; Kuick Chick Hong; Jain Sudhanshi; Lian Derrick; Wagner Elizabeth; Zou Yuhan; Ganesan Visveswari; Sim Siam Wee; Lee York Tien; Chin Francis; Chan Mei Yoke; Tan Ah Moy; Teh Bin Tean; Soh Shui Yen; Chang Kenneth T E; Loh Amos H P (2019)

144 (6); 1234-1242

Pro-metastatic and mesenchymal gene expression signatures characterize circulating tumor cells of neuroblastoma patients with bone marrow metastases and relapse.

Frontiers in oncology – Loh Amos H P; Angelina Clara; Wong Meng Kang; Tan Sheng Hui; Sukhatme Sarvesh A; Yeo Trifanny; Lim Su Bin; Lee York Tien; Soh Shui Yen; Leung Wing; Chang Kenneth T E; Chua Yong Wei; Alkaff Syed M F; Lim Tony K H; Lim Chwee Teck; Chen Zhi Xiong (2022)

12

Exosomal mRNA Cargo are biomarkers of tumor and immune cell populations in pediatric osteosarcoma.

Translational oncology – Ong Jonathan Lian K; Jalaludin Nur Fatimah Farzanah; Wong Meng Kang; Tan Sheng Hui; Angelina Clara; Sukhatme Sarvesh A; Yeo Trifanny; Lim Chwee Teck; Lee York Tien; Soh Shui Yen; Lim Tony K H; Tay Timothy Kwang Yong; Chang Kenneth Tou En; Chen Zhi Xiong; Loh Amos Hp (2024)

46

Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities.

Cancer cell – Sun Claire Xin; Daniel Paul; Bradshaw Gabrielle; Shi Hui; Loi Melissa; Chew Nicole; Parackal Sarah; Tsui Vanessa; Liang Yuqing; Koptyra Mateusz; Adjumain Shazia; Sun Christie; Chong Wai Chin; Fernando Dasun; Drinkwater Caroline; Tourchi Motahhareh; Habarakada Dilru; Sooraj Dhanya; Carvalho Diana; Storm Phillip B; Baubet Valerie; Sayles Leanne C; Fernandez Elisabet; Nguyen Thy; Pörksen Mia; Doan Anh; Crombie Duncan E; Panday Monty; Zhukova Nataliya; Dun Matthew D; Ludlow Louise E; Day Bryan; Stringer Brett W; Neeman Naama; Rubens Jeffrey A; Raabe Eric H; Vinci Maria; Tyrrell Vanessa; Fletcher Jamie I; Ekert Paul G; Dumevska Biljana; Ziegler David S; Tsoli Maria; Syed Sulaiman Nur Farhana; Loh Amos Hong Pheng; Low Sharon Yin Yee; Sweet-Cordero E Alejandro; Monje Michelle; Resnick Adam; Jones Chris; Downie Peter; Williams Bryan; Rosenbluh Joseph; Gough Daniel; Cain Jason E; Firestein Ron (2023)

41 (4); 660-677.e7

Notch-dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology.

Science immunology – Kvedaraite Egle; Milne Paul; Khalilnezhad Ahad; Chevrier Marion; Sethi Raman; Lee Hong Kai; Hagey Daniel W; von Bahr Greenwood Tatiana; Mouratidou Natalia; Jädersten Martin; Lee Nicole Yee Shin; Minnerup Lara; Tan Yingrou; Dutertre Charles-Antoine; Benac Nathan; Hwang You Yi; Lum Josephine; Loh Amos Hong Pheng; Jansson Jessica; Teng Karen Wei Weng; Khalilnezhad Shabnam; Xu Weili; Resteu Anastasia; Tey Hong Liang; Guan Ng Lai; Larbi Anis; Howland Shanshan Wu; Arnell Henrik; Andaloussi Samir E L; Braier Jorge; Rassidakis Georgios; Galluzzo Laura; Dzionek Andrzej; Henter Jan-Inge; Chen Jinmiao; Collin Matthew; Ginhoux Florent (2022)

7 (78);

Massively parallel single-molecule telomere length measurement with digital real-time PCR.

Science advances – Luo Yongqiang; Viswanathan Ramya; Hande Manoor Prakash; Loh Amos Hong Pheng; Cheow Lih Feng (2020)

6 (34);

Targeting the DNA repair pathway in Ewing sarcoma.

Cell reports – Stewart Elizabeth; Goshorn Ross; Bradley Cori; Griffiths Lyra M; Benavente Claudia; Twarog Nathaniel R; Miller Gregory M; Caufield William; Freeman Burgess B; Bahrami Armita; Pappo Alberto; Wu Jianrong; Loh Amos; Karlström Åsa; Calabrese Chris; Gordon Brittney; Tsurkan Lyudmila; Hatfield M Jason; Potter Philip M; Snyder Scott E; Thiagarajan Suresh; Shirinifard Abbas; Sablauer Andras; Shelat Anang A; Dyer Michael A (2014)

9 (3); 829-841

Histone variant H3.3 promotes metastasis in alveolar rhabdomyosarcoma.

The Journal of pathology – Karthik Nandini; Lee Jane Jia Hui; Soon Joshua Ling Jun; Chiu Hsin Yao; Loh Amos Hong Pheng; Ong Derrick Sek Tong; Tam Wai Leong; Taneja Reshma (2023)

259 (3); 342-356

BRD4 isoforms have distinct roles in tumour progression and metastasis in rhabdomyosarcoma.

EMBO reports – Das Dipanwita; Leung Jia Yu; Balamurugan Shivaranjani; Tergaonkar Vinay; Loh Amos Hong Pheng; Chiang Cheng-Ming; Taneja Reshma (2024)

25 (2); 832-852

Mitochondrial calcium uptake regulates tumour progression in embryonal rhabdomyosarcoma.

Cell death & disease – Chiu Hsin Yao; Loh Amos Hong Pheng; Taneja Reshma (2022)

13 (4);

XAF1 promotes neuroblastoma tumor suppression and is required for KIF1Bβ-mediated apoptosis.

Oncotarget – Choo Zhang'e; Koh Rachel Yu Lin; Wallis Karin; Koh Timothy Jia Wei; Kuick Chik Hong; Sobrado Veronica; Kenchappa Rajappa S; Loh Amos Hong Pheng; Soh Shui Yen; Schlisio Susanne; Chang Kenneth Tou-En; Chen Zhi Xiong (2016)

7 (23);

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.

Clinical cancer research : an official journal of the American Association for Cancer Research – Gupte Ankita; Baker Emma K; Wan Soo-San; Stewart Elizabeth; Loh Amos; Shelat Anang A; Gould Cathryn M; Chalk Alistair M; Taylor Scott; Lackovic Kurt; Karlström Åsa; Mutsaers Anthony J; Desai Jayesh; Madhamshettiwar Piyush B; Zannettino Andrew C W; Burns Chris; Huang David C S; Dyer Michael A; Simpson Kaylene J; Walkley Carl R (2015)

21 (14); 3216-3292

Ectopic CD137 expression by rhabdomyosarcoma provides selection advantages but allows immunotherapeutic targeting.

Oncoimmunology – Lee Kang Yi; Wong Hiu Yi; Zeng Qun; Le Lin Jia; Cheng Man Si; Kuick Chik Hong; Chang Kenneth Tou En; Loh Amos Hong Pheng; Schwarz Herbert (2021)

10 (1);

Targeting RNA Polymerase I Transcription Activity in Osteosarcoma: Pre-Clinical Molecular and Animal Treatment Studies.

Biomedicines – Kang Chang-Won; Blackburn Anneke C; Loh Amos Hong Pheng; Hong Kuick Chick; Goh Jian Yuan; Hein Nadine; Drygin Denis; Parish Chris R; Hannan Ross D; Hannan Katherine M; Coupland Lucy A (2023)

11 (4);

Mutations of 1p genes do not consistently abrogate tumor suppressor functions in 1p-intact neuroblastoma.

BMC cancer – Kuick Chik Hong; Tan Jia Ying; Jasmine Deborah; Sumanty Tohari; Ng Alvin Y J; Venkatesh Byrrappa; Chen Huiyi; Loh Eva; Jain Sudhanshi; Seow Wan Yi; Ng Eileen H Q; Lian Derrick W Q; Soh Shui Yen; Chang Kenneth T E; Chen Zhi Xiong; Loh Amos H P (2022)

22 (1);