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Low Lian Leng

Associate Professor

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Education Qualifications: MBBS, MMed (Fam Med), MCI, FCFP(S), FAMS

Assoc Prof Low Lian Leng is currently a Consultant at the Department of Family Medicine and Continuing Care at the Singapore General Hospital, and Medical Director at Outram Community Hospital. Concurrently, he is also Director of the Population Health and Integrated Care Office in SGH, Director, SingHealth Office of Regional Health System for SGH campus, and Director of Health Services and Outcomes Research for the SingHealth Duke-NUS Family Medicine Academic Clinical Programme. He is also faculty at the SingHealth Family Medicine Residency program and Duke-NUS Family Medicine clerkship.

Assoc Prof Low completed his Master of Clinical Investigation at the National University of Singapore and has a deep interest in health services research, especially in the areas of population health, innovative integrated care delivery models, value-based care and data analytics. He is currently the Co-Director of the Centre for Population health research and Implementation in SingHealth, and is theme lead and core lead of the Complex needs and data analytics core respectively in the SingHealth Regional Health System Population Health centre grant. The SingHealth population health research database tracks critical population health indicators and outcomes in the Regional Health System (RHS) based on the Quadruple Aim. As core lead of the Data Analytics platform in the SingHealth PULSES centre grant, Assoc Prof Low is supervising data analysts, research associates in their professional work. Concurrently, he is mentoring third year Duke-NUS medical students, family medicine residents and fellows for their research projects.

Professional Appointments and Committee Memberships:

Co-Director, Centre for Population Health Research and Implementation, SingHealth Regional Health System (2022-Present)
Chief Medical Informatics Officer, SingHealth Regional Health System (2021-Present)
Fellow, Academy of Medicine Singapore (2018-Present)
Member, Asia-Pacific Primary Care Group (AAPCG) (2018-Present)
Ordinary member, Singapore Medical Association (2006-Present)
Honorary Assistant Treasurer, College of Family Physicians Singapore (2021-Present)

Awards:

NMRC HPHSR Clinician Scientist Award (2022)
AM-ETHOS Learning Enhancement and Progress Award (LEAP) (2021, 2019)
SingHealth Excellence Awards 2021 - Distinguished Team Award (2021)
Singapore Medical Journal Best Research Paper 2019- Second prize (2019)
NUS Young Alumnus of the Year (2018)
SingHealth Publish! Award (2017)
SingHealth Duke-NUS Medicine ACP Programme-Nurturing Clinician Scientist Award (2016)
MOH-NRF Healthcare Research Scholarship (MCI) (2014)
Dean's List, Yong Loo Lin School Of Medicine (2004, 2003)

Leadership positions / roles in Education: 

Core faculty, SingHealth Residency Leadership Programme
Physician faculty, SingHealth Family Medicine Residency Programme

Research Interests: Population Health, Integrated Care, Chronic Disease Management, Patient Empowerment, Machine Learning, Data Analytics, Health Services and Systems Research, Health and Social Care

Selected Publications:  

Seng JJ, Kwan YH, Lee VS, Tan CS, Zainudin SB, Thumboo J, Low LL. Differential health care use, diabetes-related complications, and mortality among five unique classes of patients with type 2 diabetes in Singapore: a latent class analysis of 71,125 patients. Diabetes Care. 2020 May 1;43(5):1048-56.

Kwan YH, Cheng TY, Yoon S, Ho LY, Huang CW, Chew EH, Thumboo J, Østbye T, Low LL. A systematic review of nudge theories and strategies used to influence adult health behaviour and outcome in diabetes management. Diabetes & Metabolism. 2020 Nov 1;46(6):450-60.

Kwan Y, Weng S, Loh D, Phang J, Oo L, Blalock D, Chew E, Yap K, Tan C, Yoon S, Fong W, Østbye T, Low L, Bosworth H, Thumboo J. Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review. J Med Internet Res 2020;22(10):e19179

Kwan Y, Oo L, Loh D, Phang J, Weng S, Blalock D, Chew E, Yap K, Tan C, Yoon S, Fong W, Østbye T, Low L, Bosworth H, Thumboo J. Development of an Item Bank to Measure Medication Adherence: Systematic Review. J Med Internet Res 2020;22(10):e19089

Lim KK, Lee VS, Tan CS, Kwan YH, Lim ZH, Wee HL, Østbye T, Low LL. Examining the heterogeneity in excess risks of coronary heart disease, stroke, dialysis, and lower extremity amputation associated with type 2 diabetes mellitus across demographic subgroups in an Asian population: A population-based matched cohort study. Diabetes Research and Clinical Practice. 2021 Jan 1;171:108551.

Low LL, Kwan YH, Ko MS, Yeam CT, Lee VS, Tan WB, Thumboo J. Epidemiologic characteristics of multimorbidity and sociodemographic factors associated with multimorbidity in a rapidly aging Asian country. JAMA network open. 2019 Nov 1;2(11):e1915245-.

Yan S, Kwan YH, Thumboo J, Low LL. Characteristics and health care utilization of different segments of a multiethnic Asian population in Singapore. JAMA network open. 2019 Sep 4;2(9):e1910878-.

Peh KQ, Kwan YH, Goh H, Ramchandani H, Phang JK, Lim ZY, Loh DH, Østbye T, Blalock DV, Yoon S, Bosworth HB, Low LL, Thumboo J. An adaptable framework for factors contributing to medication adherence: results from a systematic review of 102 conceptual frameworks. Journal of general internal medicine. 2021 Sep;36(9):2784-95.

Low LL, Lee KH, Hock Ong ME, Wang S, Tan SY, Thumboo J, Liu N. Predicting 30-day readmissions: performance of the LACE index compared with a regression model among general medicine patients in Singapore. BioMed research international. 2015 Oct;2015.

Low LL, Vasanwala FF, Ng LB, Chen C, Lee KH, Tan SY. Effectiveness of a transitional home care program in reducing acute hospital utilization: a quasi-experimental study. BMC Health Services Research. 2015 Dec;15(1):1-8.

Lim H, Lee J, Lim M, Teo L, Sin N, Lim R, Chua S, Yeo J, Ngiam N, Tey A, Tham C, Ng K, Low L, Tang K. Bridging Connectivity Issues in Digital Access and Literacy: Reflections on Empowering Vulnerable Older Adults in Singapore. JMIR Aging 2022;5(2):e34764

Low LL, Kwan YH, Ma CA, Yan S, Chia EH, Thumboo J. Predictive ability of an expert-defined population segmentation framework for healthcare utilization and mortality-a retrospective cohort study. BMC health services research. 2019 Dec;19(1):1-8.

Seng JJ, Lim VZ, Kwan YH, Thumboo J, Low LL. Outpatient primary and tertiary healthcare utilisation among public rental housing residents in Singapore. BMC health services research. 2019 Dec;19(1):1-8.

Aw J, Seah SS, Seng BJ, Low LL. COVID-19-Related Vaccine Hesitancy among Community Hospitals’ Healthcare Workers in Singapore. Vaccines. 2022 Mar 30;10(4):537.

Aw J, Seng JJ, Seah SS, Low LL. COVID-19 vaccine hesitancy—A scoping review of literature in high-income countries. Vaccines. 2021 Aug 13;9(8):900.

Seng JJ, Monteiro AY, Kwan YH, Zainudin SB, Tan CS, Thumboo J, Low LL. Population segmentation of type 2 diabetes mellitus patients and its clinical applications-a scoping review. BMC medical research methodology. 2021 Dec;21(1):1-9.

Wee LE, Low LL, Thumboo J, Chan A, Lee KH. Factors associated with emergency room visits and hospitalisation amongst low-income public rental flat dwellers in Singapore. BMC public health. 2019 Dec;19(1):1-9.

Yoon S, Goh H, Kwan YH, Thumboo J, Low LL. Identifying optimal indicators and purposes of population segmentation through engagement of key stakeholders: a qualitative study. Health research policy and systems. 2020 Dec;18(1):1-3.

Lau J, Tan DH, Wong GJ, Lew YJ, Chua YX, Low LL, Koh GC, Kwek TS, Toh SA, Tan KK. The impact of COVID-19 on private and public primary care physicians: A cross-sectional study. Journal of Infection and Public Health. 2021 Mar 1;14(3):285-9.

Banu Z, Lim KK, Kwan YH, Yap KZ, Ang HT, Tan CS, Fong W, Thumboo J, Lee KH, Ostbye T, Low LL. Anti-hypertensive medications and injurious falls in an older population of low socioeconomic status: a nested case-control study. BMC geriatrics. 2018 Dec;18(1):1-9.