Directory



Ong Sin Tiong

Professor, Signature Research Programme in Cancer & Stem Cell Biology

Assistant Dean (MD-PhD) , Graduate Studies (PhD & Accredited Programmes) Department

Duke-NUS Medical School

Bio

I completed my undergraduate and medical training at Cambridge University in the UK, and subsequently trained as a haematologist/oncologist at the University of Chicago, where I also began my laboratory research with Michelle Le Beau. My independent research career started in 2001, when I began my studies in cancer drug resistance at the University of California at Irvine. While our studies focus on chronic myeloid leukemia, the mechanistic implications of our work have been extended and validated in other human cancers, including EGFR-mutated non-small cell lung cancer, and more recently, glioblastoma and breast cancer. In 2007, I joined Duke-NUS to help build the first American-style post-baccalaureate medical school in Asia. Arising from my practice as a haematologist and medical oncologist, my research is focused on the discovery and elucidation of novel mechanisms of resistance to cancer targeted therapies, and thereby the development of therapeutic strategies to overcome clinical drug-resistance. In addition, I have been intimately involved in training the next generation of clinician scientists comprising the MD-PhD students at Duke-NUS. In my role as the Director of the Duke-NUS MD-PhD Programme, the only such dedicated programme in the country, I have established and overseen a unique curriculum that specifically caters to the clinical needs of our students during their PhD years. Our past and current service activities include membership of the Singapore Medical Council, as well as NMRC, NIH and ASH Award review panels. Our research teams have also received international awards and recognition, including career development awards from the American Society of Clinical Oncology, European Society of Hematology John Goldman Award, and election to the American Society of Clinical Investigation. 

Education

Bachelor of Medicine, Bachelor of Surgery

University of Cambridge, United Kingdom

Master (Arts - Medical Sciences Tripos)

University of Cambridge, United Kingdom

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