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Nongpiur Monisha Esther

Associate Professor

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Bio Research Publications

Education Qualifications: MBBS, MD, PhD

Dr Monisha Esther Nongpiur is a Clinician Scientist and Junior Principal Investigator at the Singapore Eye Research Institute. She balances both clinical and research related work in Glaucoma, and her main clinical research interest is primary angle closure glaucoma.  Her research is focused on a better understanding of the clinical course, risk factors/disease mechanisms, genetics, and also to develop risk assessment models for the condition. She currently holds academic appointment at Duke-NUS Medical School, Singapore as Associate Professor, Ophthalmology and Visual Science Academic Clinical Program. She is a member of the Associate Advisory Board (AAB) of the World Glaucoma Association and the WGA Education committee.

Professional Appointments and Committee Memberships:

  • Member, Education committee, World Glaucoma Association (2018 – present)
  • Member, Associate Advisory Board, World Glaucoma Association (2017 – present)
  • Member, SERI Scientific Review Panel (2011 – present)
  • Member, Delhi Ophthalmology Society (2005 – present)

Awards:

  • Clinician Scientist Award - Investigator category, National Medical Research Council (2019)
  • International Glaucoma Panel Mentorship programme (2018)
  • Transition Award, National Medical Research Council, Singapore (2016)
  • Outstanding Young Researcher Award, Singapore Eye Research Institute (2014)
  • Publish! Award (Medical Research), SingHealth (2013)
  • Travel Grant Award, The Association for Research in Vision and Ophthalmology (ARVO) (2012)
  • Best Oral Presentations Award, 2nd Annual Graduate Scientific Congress, National University of Singapore (2012)
  • Best Paper NHG Eye Institute 2nd International Ophthalmology Congress, Singapore (2009)

Leadership positions / roles in Education: 

  • World Glaucoma Association Education Committee Member


Research Interests: 

  • Ocular imaging
  • Ophthalmic genetics
  • Development of risk assessment models for angle closure glaucoma 

Selected Publications:

1. Nongpiur ME, Verma S, Tun TA, Wong TT, Perera SA, Aung T. Plateau Iris and Severity of Primary Angle Closure Glaucoma. Am J Ophthalmol. 2020;220:1-8.

2. Liu C, Nongpiur ME, Cheng CY, et al. Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci for Estimating Angle Closure Disease Severity. Ophthalmology 2020 Dec 16:S0161-6420(20)30691-6

3. Nongpiur ME, Khor CC, Cheng CY, Husain R, Boey PY, Chew A, Ho CL, Wong TT, Perera S, Wong TY, Vithana EN, Aung T. Integration of Genetic and Biometric Risk  Factors for Detection of Primary Angle Closure Glaucoma. Am J Ophthalmol. 2019 Dec;208:160-165. 

4. Nongpiur ME, Cheng CY, Duvesh R, Vijayan S, Baskaran M, Khor CC, Allen J,Kavitha S, Venkatesh R, Goh D, Husain R, Boey PY, Quek D, Ho CL, Wong TT, Perera S, Wong TY, Krishnadas SR, Sundaresan P, Aung T, Vithana EN. Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci in Patients with Early Stages of Angle-Closure Disease. Ophthalmology. 2018 May;125(5):664-670

5. Verma S, Nongpiur ME, Atalay E, Wei X, Husain R, Goh D, Perera SA, Aung T. Visual Field Progression in Patients with Primary Angle-Closure Glaucoma Using Pointwise Linear Regression Analysis. Ophthalmology. 2017 Jul;124(7):1065-1071.

6. Nongpiur ME, Aboobakar IF, Baskaran M, Narayanaswamy A, Sakata LM, Wu R, Atalay E, Friedman DS, Aung T. Association of Baseline Anterior Segment Parameters With the Development of Incident Gonioscopic Angle Closure. JAMA Ophthalmol. 2017  Mar 1;135(3):252-258

7. Nongpiur ME, Atalay E, Gong T, Loh M, Lee HK, He M, Perera SA, Aung T. Anterior segment imaging-based subdivision of subjects with primary angle-closure glaucoma. Eye (Lond). 2017 31(4):572-577

8. Atalay E, Nongpiur ME, Yap SC, Wong TT, Goh D, Husain R, Perera SA, Aung T. Pattern of Visual Field Loss in Primary Angle-Closure Glaucoma Across Different Severity Levels. Ophthalmology. 2016 Sep;123(9):1957-64. 

9. Khor CC, Do T, Jia H, Nakano M, George R, Abu-Amero K, Duvesh R, Chen LJ, Li Z, Nongpiur ME, Perera SA, Qiao C, Wong HT, Sakai H, Barbosa de Melo M, Lee MC,Chan AS, Azhany Y, Dao TL, Ikeda Y, Perez-Grossmann RA, Zarnowski T, Day AC,Jonas JB, Tam PO, Tran TA, Ayub H, Akhtar F, Micheal S, Chew PT, Aljasim LA, DadaT, Luu TT, Awadalla MS, Kitnarong N, Wanichwecharungruang B, Aung YY,Mohamed-Noor J, Vijayan S, Sarangapani S, Husain R, Jap A, Baskaran M, Goh D, Su DH, Wang H, Yong VK, Yip LW, Trinh TB, Makornwattana M, Nguyen TT, LeuenbergerEU, Park KH, Wiyogo WA, Kumar RS, Tello C, Kurimoto Y, Thapa SS, Pathanapitoon K,Salmon JF, Sohn YH, Fea A, Ozaki M, Lai JS, Tantisevi V, Khaing CC, Mizoguchi T, Nakano S, Kim CY, Tang G, Fan S, Wu R, Meng H, Nguyen TT, Tran TD, Ueno M,Martinez JM, Ramli N, Aung YM, Reyes RD, Vernon SA, Fang SK, Xie Z, Chen XY, Foo JN, Sim KS, Wong TT, Quek DT, Venkatesh R, Kavitha S, Krishnadas SR, Soumittra N,Shantha B, Lim BA, Ogle J, de Vasconcellos JP, Costa VP, Abe RY, de Souza BB, Sng CC, Aquino MC, Kosior-Jarecka E, Fong GB, Tamanaja VC, Fujita R, Jiang Y, Waseem N, Low S, Pham HN, Al-Shahwan S, Craven ER, Khan MI, Dada R, Mohanty K, Faiq MA, Hewitt AW, Burdon KP, Gan EH, Prutthipongsit A, Patthanathamrongkasem T,Catacutan MA, Felarca IR, Liao CS, Rusmayani E, Istiantoro VW, Consolandi G,Pignata G, Lavia C, Rojanapongpun P, Mangkornkanokpong L, Chansangpetch S, Chan JC, Choy BN, Shum JW, Than HM, Oo KT, Han AT, Yong VH, Ng XY, Goh SR, Chong YF, Hibberd ML, Seielstad M, Png E, Dunstan SJ, Chau NV, Bei J, Zeng YX, Karkey A, Basnyat B, Pasutto F, Paoli D, Frezzotti P, Wang JJ, Mitchell P, Fingert JH, Allingham RR, Hauser MA, Lim ST, Chew SH, Ebstein RP, Sakuntabhai A, Park KH, Ahn J, Boland G, Snippe H, Stead R, Quino R, Zaw SN, Lukasik U, Shetty R, Zahari M, Bae HW, Oo NL, Kubota T, Manassakorn A, Ho WL, Dallorto L, Hwang YH, Kiire CA, Kuroda M, Djamal ZE, Peregrino JI, Ghosh A, Jeoung JW, Hoan TS, Srisamran N, Sandragasu T, Set SH, Doan VH, Bhattacharya SS, Ho CL, Tan DT, Sihota R, Loon SC, Mori K, Kinoshita S, Hollander AI, Qamar R, Wang YX, Teo YY, Tai ES, Hartleben-Matkin C, Lozano-Giral D, Saw SM, Cheng CY, Zenteno JC, Pang CP, Bui HT, Hee O, Craig JE, Edward DP, Yonahara M, Neto JM, Guevara-Fujita ML, Xu L, Ritch R, Liza-Sharmini AT, Wong TY, Al-Obeidan S, Do NH, Sundaresan P, Tham CC, Foster PJ, Vijaya L, Tashiro K, Vithana EN, Wang N, Aung T. Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma. Nat Genet. 2016 May;48(5):556-62

10. Trikha Sameer; Saffari Ehsan; Nongpiur Monisha; Baskaran Mani; Ho Henrietta; Li Zheng; Tan Peng-Yi; Allen John; Khor Chiea-Chuen; Perera Shamira A; Cheng Ching-Yu; Aung Tin; Vithana Eranga. A Genetic Variant in TGFBR3-CDC7 Is Associated with Visual Field Progression in Primary Open-Angle Glaucoma Patients from Singapore. Ophthalmology 2015; Dec;122(12):2416-22. 

11. Nongpiur Monisha E; Khor Chiea Chuen; Jia Hongyan; Cornes Belinda K; Chen Li-Jia; Qiao Chunyan; Nair K Saidas; Cheng Ching-Yu; Xu Liang; George Ronnie; Tan Do; Abu-Amero Khaled; Perera Shamira A; Ozaki Mineo; Mizoguchi Takanori; Kurimoto Yasuo; Low Sancy; Tajudin Liza-Sharmini A; Ho Ching-Lin; Tham Clement C Y; Soto Ileana; Chew Paul T K; Wong Hon-Tym; Shantha Balekudaru; Kuroda Masako; Osman Essam A; Tang Guangxian; Fan Sujie; Meng Hailin; Wang Hua; Feng Bo; Yong Victor H K; Ting Serena M L; Li Yang; Wang Ya-Xing; Li Zheng; Lavanya Raghavan; Wu Ren-Yi; Zheng Ying-Feng; Su Daniel H; Loon Seng-Chee; Yong Vernon K Y; Allingham R Rand; Hauser Michael A; Soumittra Nagaswamy; Ramprasad Vedam L; Waseem Naushin; Yaakub Azhany; Chia Kee-Seng; Kumaramanickavel Govindasamy; Wong Tina T; How Alicia C; Chau Tran Nguyen Bich; Simmons Cameron P; Bei Jin-Xin; Zeng Yi-Xin; Bhattacharya Shomi S; Zhang Mingzhi; Tan Donald T; Teo Yik-Ying; Al-Obeidan Saleh A; Hon Do Nhu; Tai E-Shyong; Saw Seang-Mei; Foster Paul J; Vijaya Lingam; Jonas Jost B; Wong Tien-Yin; John Simon W M; Pang Chi-Pui; Vithana Eranga N; Wang Ningli; Aung Tin. ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma. PLoS genetics 2014; 10(3)

12. Nongpiur Monisha E; Haaland Benjamin A; Perera Shamira A; Friedman David S; He Mingguang; Sakata Lisandro M; Baskaran Mani; Aung Tin. Development of a score and probability estimate for detecting angle closure based on anterior segment optical coherence tomography. American journal of ophthalmology 2014; 157(1):32-38.e1. 

13. Wei Xin; Nongpiur Monisha E; de Leon Mark S; Baskaran Mani; Perera Shamira A; How Alicia C; Vithana Eranga N; Khor Chiea-Chuen; Aung Tin. Genotype-phenotype correlation analysis for three primary angle closure glaucoma-associated genetic polymorphisms. Investigative ophthalmology & visual science 2014; 55(2):1143-1888. 

14. Nongpiur Monisha E; Haaland Benjamin A; Friedman David S; Perera Shamira A; He Mingguang; Foo Li-Lian; Baskaran Mani; Sakata Lisandro M; Wong Tien Y; Aung Tin. Classification algorithms based on anterior segment optical coherence tomography measurements for detection of angle closure. Ophthalmology 2013; 120(1):48-54. 

15. Nongpiur Monisha E; Gong Tianxia; Lee Hwee Kuan; Perera Shamira A; Cheng Li; Foo Li-Lian; He Mingguang; Friedman David S; Aung Tin. Subgrouping of primary angle-closure suspects based on anterior segment optical coherence tomography parameters. Ophthalmology 2013; 120(12):2525-2313. 

16. Cornes Belinda K; Khor Chiea Chuen; Nongpiur Monisha E; Xu Liang; Tay Wan-Ting; Zheng Yingfeng; Lavanya Raghavan; Li Yang; Wu Renyi; Sim Xueling; Wang Ya-Xing; Chen Peng; Teo Yik Ying; Chia Kee-Seng; Seielstad Mark; Liu Jianjun; Hibberd Martin L; Cheng Ching-Yu; Saw Seang-Mei; Tai E-Shyong; Jonas Jost B; Vithana Eranga N; Wong Tien Y; Aung Tin. Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations. Human molecular genetics 2012; 21(2):437-445. 

17. Vithana Eranga N; Khor Chiea-Chuen; Qiao Chunyan; Nongpiur Monisha E; George Ronnie; Chen Li-Jia; Do Tan; Abu-Amero Khaled; Huang Chor Kai; Low Sancy; Tajudin Liza-Sharmini A; Perera Shamira A; Cheng Ching-Yu; Xu Liang; Jia Hongyan; Ho Ching-Lin; Sim Kar Seng; Wu Ren-Yi; Tham Clement C Y; Chew Paul T K; Su Daniel H; Oen Francis T; Sarangapani Sripriya; Soumittra Nagaswamy; Osman Essam A; Wong Hon-Tym; Tang Guangxian; Fan Sujie; Meng Hailin; Huong Dao T L; Wang Hua; Feng Bo; Baskaran Mani; Shantha Balekudaru; Ramprasad Vedam L; Kumaramanickavel Govindasamy; Iyengar Sudha K; How Alicia C; Lee Kelvin Y; Sivakumaran Theru A; Yong Victor H K; Ting Serena M L; Li Yang; Wang Ya-Xing; Tay Wan-Ting; Sim Xueling; Lavanya Raghavan; Cornes Belinda K; Zheng Ying-Feng; Wong Tina T; Loon Seng-Chee; Yong Vernon K Y; Waseem Naushin; Yaakub Azhany; Chia Kee-Seng; Allingham R Rand; Hauser Michael A; Lam Dennis S C; Hibberd Martin L; Bhattacharya Shomi S; Zhang Mingzhi; Teo Yik Ying; Tan Donald T; Jonas Jost B; Tai E-Shyong; Saw Seang-Mei; Hon Do Nhu; Al-Obeidan Saleh A; Liu Jianjun; Chau Tran Nguyen Bich; Simmons Cameron P; Bei Jin-Xin; Zeng Yi-Xin; Foster Paul J; Vijaya Lingam; Wong Tien-Yin; Pang Chi-Pui; Wang Ningli; Aung Tin. Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma. Nature genetics 2012; 44(10):1142-1666.